Mental Health
01 Jan 2013
Use of Quetiapine as an Add on Therapy in the Treatment of Post Traumatic Stress Disorder
The purpose of this study is to evaluate how effective quetiapine versus placebo is when added to an existing therapy, in reducing the symptoms of PTSD. Official Title A Multicentre, Parallel Group, Randomised, Double Blind, Placebo Controlled Study of the Use of Quetiapine as an Add on Therapy in the…
Mental Health
01 Jan 2013
Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder (ONYX)
To evaluate the efficacy of quetiapine fumarate sustained release (Seroquel SR) in combination with an antidepressant versus an antidepressant alone in patients with Major Depressive Disorder. Official Title A Multi-Centre, Double-Blind, Randomised, Parallel-Group, Placebo-Controlled Phase III Study of the Efficacy and Safety of Quetiapine Fumarate Sustained Release (Seroquel SRTM) in…
Research and Trials
01 Jan 2013
The Neurobiology of Depressive Illness
We aim to determine why patients with depression are at an elevated risk for the development of coronary heart disease, and resolve whether the severity of a patient’s depression has a counterpart in demonstrable abnormalities in brain chemistry. Official Title The Neurobiology of Depressive Illness: Causes and Consequences of Altered…
Mental Health
01 Jan 2013
The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study
The aim of the project is to investigate the use of raloxifene (a new form of estrogen) as a treatment for schizophrenia in postmenopausal women. Official Title The Use of Selective Estrogen Receptor Modulators in the Treatment of Schizophrenia- a Pilot Study Conditions Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder Study Type…
Mental Health
01 Jan 2013
A Study of Risperidone Long-Acting Injection Versus Oral Antipsychotics in Schizophrenia Patients With a History of Being Poorly Compliant With Taking Their Medication
The purpose of this study is to evaluate risperidone long-acting injection (an antipsychotic medication) versus oral antipsychotics in schizophrenia patients with a history of being poorly compliant with taking their medication. Official Title Pragmatic Randomized Trial of ‘Risperdal CONSTA’ (Risperidone) Versus Oral Atypical Antipsychotics in Poorly Adherent Subjects With Schizophrenia…
Research and Trials
01 Jan 2013
Effect of the ‘Mother and Baby’ Program on Well-Being
The study investigates the effect of the ‘Mother and Baby’ (M&B) program on the psychological health and well-being of new mothers 6-10 weeks following the birth of their baby. The M&B program is an 8-week program of group exercise and education sessions provided by various health professionals. The design of…
Mental Health
01 Jan 2013
Study Evaluating the Safety, Tolerability, and Efficacy of Lecozotan SR in Outpatients With Alzheimer’s Disease
The purpose of the study is to determine the safety, tolerability, and efficacy of 3 doses of lecozotan in combination with a cholinesterase inhibitor in patients with mild to moderate Alzheimer’s disease (AD). Official Title A 6-Month, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Safety, Tolerability, and Efficacy Study of 3 Doses of…
Mental Health
01 Jan 2013
Prospective Research in Memory Clinics (PRIME), a Disease Registry for Current Management of Treatment and Outcome in Patients With Dementia (or Alzheimer’s).
The purpose of the PRIME (Prospective Research in Memory Clinics) Study is to examine the current management and outcomes of patients with dementia. Approximately 4500 subjects will be enrolled in this disease registry across 12 sites in Australia. Clinical, treatment, health status and economic data will be acquired over 3…
Mental Health
01 Jan 2013
Treatment of Comorbid Depression and Substance Abuse in Young People
This study aims to treat young people with an adjunctive integrated Cognitive Behaviour Therapy (CBT) intervention and to examine the acceptability of this treatment approach within this population. The study will also include a pilot placebo-controlled trial of sertraline for those young people who fail to or only partially respond…
