Mental Health
01 Jan 2013
Trial for the Treatment of Alcohol Dependence
The purpose of this study is to compare the effectiveness of two anti-craving medications, naltrexone versus acamprosate, in the treatment of alcohol dependence. Official Title The Role of Pharmacotherapy in Prevention of Relapse in Alcohol Dependence Conditions Alcoholism Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment,…
Mental Health
01 Jan 2013
An Open-Label Extension Study Of Lamotrigine In Subjects With Bipolar Disorder
The precursor study (SCA101469) was an open-label, prospective multicentre study in adult subjects diagnosed with bipolar disorder consisting of 36 weeks treatment with lamotrigine. The current study is to provide 12 months post study access to open-label lamotrigine for participants of the SCA101469 study. Official Title An Open-Label Extension Study…
Mental Health
01 Jan 2013
Transcranial Magnetic Stimulation for Bipolar Depression
This is a study to assess the effectiveness of repetitive transcranial magnetic stimulation (rTMS) as a treatment for depressed adults with bipolar disorder. Official Title A Comparison of Left vs. Right Prefrontal Cortex Transcranial Magnetic Stimulation as a Treatment for Bipolar Depression Conditions Bipolar Depression Study Type Interventional Study Design…
Children's health
01 Jan 2013
Long-Term, Open Label Atomoxetine Study on Attention Deficit Hyperactivity Disorder
To learn about the safety and any side effects of atomoxetine when given to children and adolescents for about 5 years (long-term) and to learn whether atomoxetine can help children and adolescents with ADHD who take the drug for about 5 years (long-term). Official Title Long-Term, Open Label Safety Study…
Mental Health
01 Jan 2013
A Comparison of Duloxetine Hydrochloride, Marketed Comparator, and Placebo in the Treatment of Generalized Anxiety Disorder
This is a clinical trial assessing duloxetine and comparator to placebo in patients who have generalized anxiety disorder. Official Title A Comparison of Duloxetine Hydrochloride, Venlafaxine Extended Release, and Placebo in the Treatment of Generalized Anxiety Disorder Conditions Generalised Anxiety Disorder Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo…
Heart
01 Jan 2013
Panic Disorder and Cardiac Risk
The reason for increased cardiac mortality in panic disorder has not been precisely identified, but possibly is due to chronic activation of the cardiac stimulant (sympathetic) nerves, which may predispose the individual with panic disorder to disorders of cardiac rhythm and coronary artery spasm. The uniqueness of this study lies…
Mental Health
01 Jan 2013
An Eight-Week Study to Evaluate the Efficacy and Safety of 2 Doses of Saredutant in Patients With Generalized Anxiety Disorder
The primary objective is to evaluate the efficacy of two fixed doses (100 mg and 30 mg once daily) of saredutant compared to placebo in patients with generalized anxiety disorder. The secondary objectives are to evaluate the efficacy of saredutant on disability and quality of life in patients with generalized…
Gastro
01 Jan 2013
A Study to Evaluate the Efficacy and Safety of CCX282-B in Subjects With Moderate to Severe Crohn’s Disease
The purpose of this study is to determine whether CCX282-B is effective in treating patients with moderate to severe Crohn’s Disease. Official Title A Multinational, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of CCX282-B in Subjects With Moderate to Severe Crohn’s Disease Conditions Crohn’s Disease…
Cancer
01 Jan 2013
A Single Arm Trial of Oxaliplatin and 5FU With Concurrent Radiation in Patients With Metastatic Rectal Cancer
This trial is a single-arm study for patients presenting with both local and metastatic adenocarcinoma of rectum. The aims of the trial are (1) to determine the tolerability rate, and (2) to determine toxicity rates, pelvic and distant response rates in patients with locally advanced rectal cancer in the presence…
