The purpose of this study is to evaluate how effective quetiapine versus placebo is when added to an existing therapy, in reducing the symptoms of PTSD.
Official Title
A Multicentre, Parallel Group, Randomised, Double Blind, Placebo Controlled Study of the Use of Quetiapine as an Add on Therapy in the Treatment of Post Traumatic Stress Disorder
Conditions
Post-Traumatic Stress Disorder
Study Type
Interventional
Study Design
Treatment, Randomized, Double-Blind, Placebo Control, Single Group Assignment, Efficacy Study
Further Details
Primary Outcome Measures:
- Clinical Administered PTSD Scale (CAPS2)
Secondary Outcome Measures:
- Hamilton Depression Scale (HAM-D)
- Hamilton Anxiety Scale (HAM-A)
- Posttraumatic Stress Disorder Checklist (PCL)
- Clinical Global Impressions (CGI)
Study Start
December 2004
Eligibility & Criteria
- Ages Eligible for Study: 18 Years – 65 Years
- Genders Eligible for Study: Both
Inclusion Criteria:
- Hospitalised and non-hospitalised patients / Veteran or Civilian / Have had symptoms of PTSD for a minimum of 12 months prior to giving consent to the study
Exclusion Criteria:
- History of psychotic condition / quetiapine or other anti-psychotics not worked previously / Taking prohibited medications (mood stabilizers / substance abuse)
Total Enrolment
90
Contact Details
- Brisbane, Queensland, Australia; Recruiting
- Adelaide, South Australia, Australia; Recruiting
- Melbourne, Victoria, Australia; Recruiting
Contact AstraZeneca for more information
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