Research and Trials

Cancer 04 Nov 2018

New resource helps families assess childhood cancer clinical trials

UNSW medical researchers are developing a tool to support families who are deciding whether to enrol in a childhood cancer clinical trial.

Children's health 27 Sep 2017

Learning to improve foot control in cerebral palsy

A device to measure foot control is being trialled to improve walking ability for adolescents and young adults with cerebral palsy.

Cancer 04 Jul 2014

ICON8: An international phase III randomised trial of dose-fractionated chemotherapy compared to standard three-weekly chemotherapy, following immediate primary surgery or as part of delayed primary surgery, for women with newly diagnosed epithelial ovarian, fallopian tube or primary peritoneal cancer

Short title ICON8 (Australia New Zealand Gynaecological Oncology Group trial number ANZGOG14) Summary ICON8 is a randomised (1:1:1 ratio), three-arm, three stage Gynaecologic Cancer InterGroup (GCIG) phase III trial designed to evaluate the safety and efficacy of dose-dense, dose-fractionated carboplatin-paclitaxel chemotherapy in the first-line treatment of ovarian cancer. Official title…

Heart 01 Jan 2013

CAROLINA: Cardiovascular Outcome Study of Linagliptin versus Glimepiride in Patients with Type 2 Diabetes

The aim of the study is to investigate the long-term impact on cardiovascular morbidity and mortality, relevant efficacy parameters (e.g., glycaemic parameters) and safety (e.g., weight and hypoglycaemia) of treatment with linagliptin in patients with type-2 diabetes at elevated cardiovascular risk receiving usual care, and compare outcome against glimepiride. Official…

Cancer 01 Jan 2013

The Safety Evaluation of the GSK-580299 Vaccine in Women from the Control Group in the Primary NCT00294047 Study

This extension study is designed to assess the safety of GSK Biological’s HPV vaccine GSK580299 in female subjects who took part in the primary study NCT00294047 and received the control vaccine in countries for which the licensed GSK HPV vaccine is not indicated for the subject’s age group (26 years…

Children's health 01 Jan 2013

Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques (IMPART)

This study is to compare the effects of high-fat overfeeding on metabolic risk factors in children born through assisted reproduction technologies (ART) versus children conceived naturally (controls). We will utilise state of the art measures to characterise the physiological, endocrine and molecular responses to high fat overfeeding. The investigators…

Blood 01 Jan 2013

Nasal Application of 5% Tea Tree Oil (TTO) Versus Mupirocin for the Prevention of Catheter-associated Infections in Renal Dialysis Patients

This study will compare the use of tea tree oil against mupirocin as a topical nasal antiseptic to see which is best at preventing infections in patients that need renal dialysis. Fifty subjects will be recruited into each arm of the trial and will be assessed for signs of infection…

Lungs 01 Jan 2013

A Study of LY2127399 in Patients with Systemic Lupus Erythematosus

The purpose of this SLE study is to evaluate the efficacy, safety and tolerability of two different doses of LY2127399 administered in addition to standard of care therapy in patients with active SLE. Official Title A Phase 3, Multicenter, Randomised, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of…

Research and Trials 01 Jan 2013

Study to Evaluate the Long-term Efficacy and Safety of Oral Tolvaptan Tablet Regimens in Subjects with Autosomal Dominant Polycystic Kidney Disease

To demonstrate whether tolvaptan modifies ADPKD progression as measured by changes from baseline (from trial 156-04-251) in total kidney volume (TKV) and renal function. Official Title Multi-center, Open-label, Extension Study to Evaluate the Long-term Efficacy and Safety of Oral Tolvaptan Tablet Regimens in Subjects With Autosomal Dominant Polycystic Kidney Disease…