Infections
01 Jan 2013
Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria
This is a double blinded study where 2 test vaccines will be evaluated to see if they protect persons who have never had malaria against malaria infection when bitten by mosquitoes. Official Title Conditions Malaria Study Type Intervention Study Design Prevention, Randomized, Double-Blind, Active Control, Single Group Assignment, Safety/Efficacy Study…
Infections
01 Jan 2013
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers with HIV
HIV infected women in South Africa have a high risk of tuberculosis (TB) infection. Children born to HIV infected mothers may be more likely to be exposed to and become infected with TB, and children infected with TB have a higher risk of developing severe disease than adults with TB.
Infections
01 Jan 2013
Treating Severe Chronic Epstein-Barr Virus (EBV) Infection with EBV Specific Cytotoxic T Lymphocytes (CTLs)
Severe chronic active Epstein-Barr virus (SCAEBV) is a rare Epstein-Barr virus (EBV or commonly known as mono or the kissing disease) associated disorder. This disorder may cause chronic tiredness and fevers and sometimes be complicated by life threatening problems such as multi-organ failure, chronic (ongoing) pneumonia, and lymphoproliferative diseases (diseases…
Infections
01 Jan 2013
Efficacy and Safety of Nasonex vs. Placebo in Subjects with SAR and Concomitant Asthma
An association between seasonal allergic rhinitis (SAR) and allergic asthma has been established through epidemiologic, pathophysiologic, and therapeutic studies. This study will compare Nasonex Nasal Spray to Placebo in treating the nasal and asthma symptoms experienced by subjects with SAR and concomitant asthma. Official Title Conditions – Rhinitis, Allergic, Seasonal-…
Infections
01 Jan 2013
IVIG – West Nile encephalitis: Safety and Efficacy
Primary To assess and characterize the safety and tolerability of Omr-IgG-am in a population of hospitalized patients with confirmed or suspected WNV disease Official Title A Phase I/II Randomized, Placebo-controlled Trial to Assess the Safety and Efficacy of Intravenous Immunoglobulin G (Omr-IgG-am) Containing High Anti-West Nile Virus Antibody Titers in…
Infections
01 Jan 2013
Vitamin A Therapy for Tuberculosis
The study will determine whether a daily vitamin and mineral supplement (a multivitamin including Vitamin A) will improve health when added to standard chemotherapy for tuberculosis. This study will compare the effectiveness of the multivitamin in HIV infected and HIV uninfected patients. Official Title Adjunct Vitamin A Therapy for Tuberculosis…
Infections
01 Jan 2013
Resistance to HIV Infection
The immune systems of some individuals may be capable of resisting HIV infection. These individuals do not appear to be infected with HIV despite multiple sexual encounters with HIV infected partners. This study will examine the immune systems of these individuals to determine what factors are responsible for their ability…
Infections
01 Jan 2013
Immune Function of Infants with HIV
This observational study will evaluate data from infants born to HIV infected mothers in order to better characterize disease progression in early HIV infection. Official Title Killer Cells and Viral Load in Vertical HIV Infection Conditions HIV Infections Study Type Observational Study Design Natural History, Longitudinal, Defined Population, Retrospective/Prospective Study…
Infections
01 Jan 2013
Antibody Production in Immune Disorders
This study will evaluate immune function in people with a known or suspected immune disorder. It will determine participants’ immune response to vaccines by measuring blood antibody levels after vaccination. Official Title Evaluation of Antibody Production in Primary Immune Disorders Conditions – Immunologic Disease Study Type Observational Study Design Natural…
