Infections
01 Jan 2013
Peg-Intron for Prevention of Disease Progression in Chronic Hepatitis C Patients with Cirrhosis who failed with a Interferon plus Ribavirin Therapy
The objective of the study is to evaluate the safety and efficacy of PEG-Intron vs. no treatment for the prevention of disease progression in adult subjects with compensated cirrhosis secondary to chronic hepatitis C, who failed to respond to therapy with an a interferon plus ribavirin. Official Title Conditions –…
Infections
01 Jan 2013
Genetics of Hepatitis C Virus Infection
The course of hepatitis C varies among people infected with the virus. Some people respond to treatment while many do not; some recover completely while others remain chronically infected; and among those who remain infected, some have mild symptoms while others’ symptoms are severe. This study will look for genetic…
Infections
01 Jan 2013
Long-Term Therapy with Ribavirin for Chronic Hepatitis C
Chronic hepatitis C is a disease of the liver caused by the hepatitis C virus. The disease can be serious and even fatal. Approximately 25% of patients with chronic hepatitis C will develop cirrhosis and some of these patients will develop cancer of the liver or liver failure. Official Title…
Bone
01 Jan 2013
Effects of HIV on the Development and Function of Bone Marrow Cells
This study will examine the effects of HIV on bone marrow cells. Various types of cells from bone marrow will be studied to learn which cells become infected with HIV, what changes occur in the number of or growth patterns of the cells, what kinds of proteins the cells make…
Infections
01 Jan 2013
Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection
This study will evaluate hepatitis C virus (HCV) infection in blood donors who test positive for antibodies to this virus. Most HCV-infected people do not become ill and are not aware that they have hepatitis or have had it in the past. Some infected people recover completely, whereas others remain…
Infections
01 Jan 2013
A Study of Patients Who Recently Have Been Infected with HIV
The purpose of this study is to find out if anti-HIV drugs, taken by patients who are newly infected with HIV, can make the level of HIV in the body too low to detect. Studying patients who recently have been infected with HIV may help researchers understand how HIV infection…
Infections
01 Jan 2013
Pegasys in Combination with Copegus in Previously Untreated Patients with Chronic Hepatitis C Virus Genotype 2 or 3
The objective of this study is to evaluate the efficacy and safety of Pegasys in combination with Copegus given for 16 weeks versus 24 weeks in previously untreated patients with Chronic Hepatitis C virus Genotype 2 or 3. Official Title Evaluation of the efficacy and safety of Pegasys in combination…
Infections
01 Jan 2013
Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis.
The purposes of this study are to determine: 1. Whether drotrecogin alfa (activated) helps children with severe sepsis survive their condition more often or recover faster than children who do not receive drotrecogin alfa (activated). 2. Whether drotrecogin alfa (activated) minimizes long term disabilities associated with severe sepsis. 3.
Infections
01 Jan 2013
Daily Tenofovir DF to Prevent HIV Infection Among Sex Workers in Cambodia
Tenofovir disoproxil fumarate (also known as tenofovir DF or Viread) is used with other anti-HIV drugs to treat HIV infection. Taking tenofovir DF every day may also prevent HIV infection. This study will determine if taking a tenofovir DF tablet every day is safe and effective in preventing HIV infection.
