Cancer

Cancer 01 Jan 2013

Study of ONTAK in patients with B-Cell Chronic Lymphocytic Leukemia (CLL)

The purpose of this study is to evaluate the safety and effectiveness of ONTAK in previously treated patients with chronic lymphocytic leukemia (CLL) Official Title A Multicenter, Phase II Study of ONTAK (Denileukin Diftitox) in Patients with Previously-Treated Chronic Lymphocytic Leukemia Conditions – Leukemia, Lymphocytic, Chronic Study Type Interventional…
Cancer 01 Jan 2013

Assessing Quality of Life of Patients With Prostate Cancer

RATIONALE: Quality of life assessment in patients undergoing prostate cancer treatment may help determine the intermediate and long-term effects of the treatment on these patients. Official Title Study of the EORTC QLQ-C30 and Prostate Cancer-Specific QLQ-PR25 Questionnaires to Assess Quality of Life of Patients With Stage I-IV Prostate Cancer…
Cancer 01 Jan 2013

Prostatectomy Compared With Watchful Waiting in Treating Patients With Stage I or Stage II Prostate Cancer

RATIONALE: Watchful waiting until symptoms appear may be effective in patients with prostate cancer. It is not yet known if watchful waiting is more effective than prostatectomy for early prostate cancer. Official Title NCI HIGH PRIORITY CLINICAL TRIAL — Phase III Randomized Study of Prostatectomy Versus Expectant Management With Palliative…
Cancer 01 Jan 2013

XELOX versus fluorouracil/leucovorin as therapy for surgery in association with colon carcinoma

The primary purpose of the study is to show that the combination of capecitabine plus oxaliplatin (XELOX) is better than the combination of fluorouracil/leucovorin (5-FU/LV) in terms of time to cancer relapse or death in patients who have had surgery for colon cancer (Dukes stage C) and have not received…
Cancer 01 Jan 2013

Chemotherapy and Radiation Therapy in Treating Infants With Brain Tumors

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining radiation therapy with chemotherapy may kill more tumor cells. RATIONALE: Drugs used in chemotherapy use different ways to stop tumor…
Cancer 01 Jan 2013

XK469 in Treating Patients With Advanced Solid Tumors or Lymphoma

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die.PURPOSE: Phase I trial to study the effectiveness of XK469 in…
Cancer 01 Jan 2013

“REDUCE” – A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk

Purpose This 4-year study will compare how safe and effective an oral investigational medicine is (compared to placebo) in preventing the development of prostate cancer in men that are defined by the study entrance criteria as being at an increased risk for prostate cancer. Study visits to the clinic…
Cancer 01 Jan 2013

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

Purpose The are a variety of cancerous diseases of the blood and bone marrow that can be potentially cured by bone marrow transplantation (BMT). Diseases like leukemia, lymphoma, and multiple myeloma are among the conditions that can be treated with BMT. Official Title Non-myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic…
Cancer 01 Jan 2013

LIPID (Long-term Intervention with Pravastatin in Ischaemic Disease)

LIPID (Long-term Intervention with Pravastatin in Ischaemic Disease) was a large multicentre trial begun in 1990, of the effects of pravastatin in 9014 patients with coronary heart disease and average cholesterol levels. The randomised phase of the trial finished in 1997 and the results, published in 1998 in the New…