Cancer
01 Jan 2013
Selenium and Vitamin E in Preventing Prostate Cancer
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. It is not yet known which regimen of selenium and/or vitamin E may be more effective in preventing prostate cancer. RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent…
Cancer
01 Jan 2013
Video-Assisted Surgery Followed by Radiation Therapy in Treating Patients With Stage I Non-small Cell Lung Cancer and Poor Heart and Lung Function
RATIONALE: Video-assisted surgery followed by radiation therapy may be an effective treatment in patients whose poor heart and lung function make them high risk for standard surgery. RATIONALE: Video-assisted surgery followed by radiation therapy may be an effective treatment in patients whose poor heart and lung function make them high…
Cancer
01 Jan 2013
Vaginal Changes and Sexual Function in Patients With Cervical Cancer
RATIONALE: Vaginal changes that may effect sexual function occur in patients undergoing treatment for cervical cancer. Official Title Conditions Study Type Study Design Further Details Study Start Eligibility & Criteria Total Enrolment Contact Details…
Bone
01 Jan 2013
Diagnostic Study of Patients With Ewing’s Sarcoma
RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to plan more effective therapy. PURPOSE: Diagnostic trial to study genetic differences in patients who have Ewing’s sarcoma. RATIONALE: Genetic testing may help predict how cancer will respond to treatment and allow doctors to…
Cancer
01 Jan 2013
Radiation Therapy in Patients With Limited-Stage Small Cell Lung Cancer in Complete Remission
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells and prevent the spread of cancer to the brain. It is not yet known if standard-dose radiation therapy is more effective than high-dose radiation therapy in preventing the spread of limited-stage small cell lung cancer cells to the brain. Official…
Cancer
01 Jan 2013
Surgery in Treating Children With Neuroblastoma
RATIONALE: Surgery alone may be effective in treating children with neuroblastoma. PURPOSE: Phase III trial to study the effectiveness of surgery alone in treating children who have neuroblastoma. Official Title Phase III Study of Primary Surgical Therapy in Children With Low-Risk Neuroblastoma Conditions – localized resectable neuroblastoma- stage 4S neuroblastoma…
Cancer
01 Jan 2013
Irinotecan in Treating Children With Refractory Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Official Title Phase II Study of Irinotecan in Children With Refractory CNS or Solid Tumors Conditions Condition: – Ewing’s family of tumors- childhood brain tumor- childhood rhabdomyosarcoma- childhood solid tumor-…
Blood
01 Jan 2013
Study of Combination Thalidomide Plus Glucocorticoid Therapy Versus Glucocorticoid Therapy Alone as Induction Therapy for Previously Untreated Subjects with Multiple Myeloma
Randomized subjects will receive study drug, either thalidomide plus high-dose dexamethasone or placebo identical in appearance to thalidomide plus high-dose dexamethasone, in 4-week cycles. Subjects will remain on study drug until they experience disease progression or until the subject discontinues for any other reason. Subjects will have visits every cycle…
Cancer
01 Jan 2013
Bortezomib in Treating Patients With Advanced Cancer and Kidney Dysfunction
RATIONALE: Bortezomib may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. RATIONALE: Bortezomib may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth.PURPOSE: Phase I trial to study the effectiveness of bortezomib in treating patients who have…
