Lungs
01 Jan 2013
Segmental Bronchoalveolar Lavage
Bronchoalveolar lavage is a diagnostic and therapeutic procedure conducted by placing a fiberoptic scope into the lung of a patient, and injecting sterile water (saline) into the lung and removing. The sterile water removed contains secretions, cells, and protein from the lower respiratory tract. This sample can be analyzed to…
Lungs
01 Jan 2013
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to determine whether genetic factors contribute to an individuals risk of developing obstructive lung disease from smoking cigarettes. Official Title Genetic Mechanisms of Chronic Obstructive Pulmonary Disease Conditions – Chronic Obstructive Lung Disease Study Type Observational Study Design Screening, Cross-Sectional, Defined Population, Retrospective Study…
Lungs
01 Jan 2013
Sarcoid Genetic Analysis (SAGA)
To identify sarcoidosis susceptibility genes and to determine how these genes and environmental risk factors interact to cause sarcoidosis. Official Title Conditions – Lung Diseases- Sarcoidosis Study Type Observational Study Design Natural History, Defined Population Further Details BACKGROUND: Sarcoidosis is a rare systemic granulomatous disease that mainly affects…
Infections
01 Jan 2013
Investigating Severe Acute Respiratory Syndrome (SARS)
Severe Acute Respiratory Syndrome (SARS) is a newly recognized illness that can be fatal. Official Title An Investigation of the Inflammatory Response in Severe Acute Respiratory Syndrome (SARS) Conditions -SARS Virus Study Type Observational Study Design Natural History Further Details The purpose of this study is to better understand SARS…
Lungs
01 Jan 2013
Ozone and Rhinovirus-Induced Disease in Asthmatics
In the U.S., morbidity associated with human rhinovirus (RV) infection represents a major health problem. In asthmatics, up to 80% of asthma exacerbations are associated with upper respiratory infections. Despite evidence that environmental oxidant pollutants, such as ozone, may increase the severity of viral disease, the mechanisms underlying such an…
Lungs
01 Jan 2013
Effect of Ventilation-Feedback Training on Exercise Performance in COPD
The primary objective of the study is to determine whether individuals with Chronic Obstructive Pulmonary Disease (COPD) who complete ventilation-feedback training combined with a moderately-high intensity exercise and upper body strength program will demonstrate significantly longer exercise duration on a constant work rate treadmill test when compared to subjects who…
Lungs
01 Jan 2013
Role of Role of Genetic Factors in the Development of Lung Disease
This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. Official Title Role of Genetic Factors in the Pathogenesis of Lung Disease Conditions –…
Lungs
01 Jan 2013
Sample Collections from the Airways of Asthmatic Patients
Fiberoptic bronchoscopy is a procedure which involves passing a pencil-thin tube into the lung in order to collect fluid and cells from the airways. Fiberoptic bronchoscopy can collect cells from the walls of airways by gently brushing them (bronchial brushing). In addition, squirting small amounts of sterile water in to…
Lungs
01 Jan 2013
Nasal Irritation Study
This study seeks to document differences in nasal irritant sensitivity within the population. We are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant sensitivity. This is important in understanding symptom reporting patterns in air pollution situations (particularly in so-called “problem buildings”), as well as…
