Lungs
01 Jan 2013
Study Evaluating the Safety and Efficacy of Infliximab in Subjects with Moderate to Severe Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine the safety and efficacy of infliximab in patients with moderate to severe Chronic Obstructive Pulmonary Disease. Official Title A Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled Parallel Group, Dose Finding Study Evaluating the Safety and Efficacy of Infliximab Administration in Symptomatic Subjects with…
Lungs
01 Jan 2013
Study of the Disease Process of Lymphangioleiomyomatosis
Pulmonary lymphoangioleiomyomatosis (LAM) is a destructive lung disease typically affecting women of childbearing age. Currently, there is no effective therapy for the disease and the prognosis is poor. Official Title Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM) Conditions – Leiomyomatosis- Lung Disease- Pneumothorax- Tuberous Sclerosis Study Type Observational Study…
Lungs
01 Jan 2013
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)
To assess rapidly innovative treatment methods in patients with adult respiratory distress syndrome as well as those at risk of developing ARDS. To establish a network of interactive Critical Care Treatment Groups (CCTG) to establish and maintain the required infrastructure to perform multiple therapeutic trials that may involve investigational drugs,…
Lungs
01 Jan 2013
Study of Inhaled Nitric Oxide for Preterm Infants
This multicenter trial tests whether inhaled nitric oxide will reduce death or the need for oxygen at 36 weeks postmenstrual age in preterm infants with severe lung disease. Official Title Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure Conditions – Respiratory Distress Syndrome- Infant, premature- Sepsis- Pneumonia-…
Lungs
01 Jan 2013
Treatment of Pulmonary Sarcoidosis with Pentoxifylline
Sarcoidosis is a disease most commonly affecting the lungs, but it can also involve lymph nodes, skin, liver, spleen, eyes, bones, and glands. The cause of the disease is unknown. When it occurs it can produce an inflammatory reaction leading to irreversible organ damage and disability. Official Title Conditions –…
Lungs
01 Jan 2013
Lung Volume Reductions Surgery (LVRS) Study
The main objectives of this study is to see if a type of lung surgery, known as lung reduction surgery, in addition to standard medical treatment improves the quality of life, lung function, and reduces the high mortality associated with severe emphysema when compared to standard medical treatment alone. Another…
Lungs
01 Jan 2013
Tissue Collection from People with Cystic Fibrosis
This study will examine the relationship between bacterial products in lung infections in cystic fibrosis and disease severity. It will examine plasma and lung tissue from cystic fibrosis patients. Official Title Tissue Collection Protocol for Individuals with Cystic Fibrosis Conditions Cystic Fibrosis Study Type Observational Study Design Natural History…
Lungs
01 Jan 2013
Studying Patients with Cystic Fibrosis and Other Pulmonary and Pancreatic Disorders
Cystic fibrosis is a disease that affects many parts of the body, particularly the lungs and pancreas. The main purpose of this study is to further understand the natural history, clinical presentation, and genetics of cystic fibrosis. Official Title Diagnosis and Treatment of Patients with Cystic Fibrosis and Other Disorders…
Lungs
01 Jan 2013
Epidemiology of Surfactant Protein-B Deficiency
To determine the impact of surfactant protein B genetic mutations on the risk of respiratory distress syndrome in infancy. Official Title Conditions – Lung Diseases- Respiratory Distress Syndrome Study Type Observational Study Design Natural History, Case Control Further Details BACKGROUND: Respiratory distress syndrome (RDS) is a common cause…
