Infections
01 Jan 2013
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers with HIV
HIV infected women in South Africa have a high risk of tuberculosis (TB) infection. Children born to HIV infected mothers may be more likely to be exposed to and become infected with TB, and children infected with TB have a higher risk of developing severe disease than adults with TB.
Lungs
01 Jan 2013
Role of T-Cells in Asthma
This study will examine the movement of T cells (a type of white blood cell) from the blood to the lungs in patients with asthma after exposure to an allergen, such as cat dander or pollen. Asthma is in large part due to inflammation of the bronchi (the breathing tubes…
Lungs
01 Jan 2013
Childhood Asthma Research and Education (CARE) Network
To evaluate current and novel therapies and management strategies for children with asthma. The emphasis is on clinical trials that help identify optimal therapy for children with different asthma phenotypes, genotypes, and ethnic backgrounds and children at different developmental stages. Official Title Conditions – Asthma- Lung Diseases Study Type…
Lungs
01 Jan 2013
Pollutant altered allergic response
This study is designed to investigate whether exposure to particulate air pollution increases the allergic response to allergens. Research studies suggest that symptoms in individuals with allergies may be aggravated by exposure to particulate air pollution. We sought to experimental determine this by exposing human volunteers to combustion particles, a…
Lungs
01 Jan 2013
A safety and efficacy trial evaluating the use of SanOrg34006 compared to placebo in patients who have completed 6 months of treatment for symptomatic pulmonary embolism or deep vein thrombosis
Patients diagnosed with pulmonary embolism (blood clot in the lung) or deep vein thrombosis (blood clot in a leg vein) are at risk for these blood clots to reoccur. Anticoagulant (blood-thinning) drugs are normally given immediately after the clot is discovered and are continued for a period of 3 or…
Lungs
01 Jan 2013
A safety and efficacy trial evaluating the use of SanOrg34006 in the treatment of pulmonary embolism
Patients who have a pulmonary embolism (blood clot in the lung) will be treated in this study. The purpose of the study is to compare the safety and effectiveness of a new injectable anticoagulant (blood-thinning) drug, SanOrg34006, with the standard way of treating a pulmonary embolism. The standard treatment includes…
Infections
01 Jan 2013
Efficacy and Safety of Nasonex vs. Placebo in Subjects with SAR and Concomitant Asthma
An association between seasonal allergic rhinitis (SAR) and allergic asthma has been established through epidemiologic, pathophysiologic, and therapeutic studies. This study will compare Nasonex Nasal Spray to Placebo in treating the nasal and asthma symptoms experienced by subjects with SAR and concomitant asthma. Official Title Conditions – Rhinitis, Allergic, Seasonal-…
Lungs
01 Jan 2013
A study using an investigational new medicine looking at its effects on pulmonary function and respiratory symptoms in patients with chronic obstructive pulmonary disease (COPD)
Treatment with an investigational new medicine to determine if it improves lung function and decreases the symptoms of patients with chronic obstructive pulmonary disease (COPD) Official Title Conditions – Chronic Obstructive Pulmonary Disease Study Type Interventional Study Design Treatment Further Details Study Start Eligibility & Criteria Ages Eligible…
Lungs
01 Jan 2013
Respiratory Syncytial Virus (RSV) Bronchiolitis Study
The purpose of this study is to look at whether an investigational drug can treat the breathing symptoms of RSV bronchiolitis in children 6 to 18 months of age. Official Title Conditions – Bronchiolitis Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study…
