Heart
01 Jan 2013
Air Pollution and Implantable Cardioverter Defibrillators
Community based studies have shown increased cardiovascular mortality associated with acute exposures to particulate air pollution. Electrocardiographic changes have also been reported in animals exposed to particles in controlled conditions. We have hypothesized that cardiovascular patients may experience life-threatening arrhythmias associated with particulate air pollution episodes. Implanted cardioverter defibrillator (ICD)…
Heart
01 Jan 2013
Telephone Intervention in Heart Failure Patients
The primary hypothesis of this study is that Heart Failure Telephone Intervention (HearT-I) will decrease hospitalizations and clinic visits in the veteran population with heart failure. Official Title Randomized Trial of a Telephone Intervention in Heart Failure Patients Conditions – Heart Failure, Congestive- Cardiomyopathy Study Type Interventional Study Design…
Blood
01 Jan 2013
Magnetic Resonance Imaging of the Blood Vessels of the Heart
This study is directed at evaluating patients with “myocardial ischemia” or poor blood supply to the heart muscle due to coronary artery disease. The major objective of this study is to determine the level of safety and effectiveness of magnetic resonance imaging at diagnosing coronary artery disease. In addition, this…
Heart
01 Jan 2013
Evaluation of Patients with Known or Suspected Heart Disease
In this study researchers will admit and evaluate patients with known or suspected heart disease referred to the Cardiology Branch of the National Heart, Lung, and Blood Institute (NHLBI). Official Title Evaluation of Patients with Known or Suspected Heart Disease (Screening Protocol) Conditions – Chest Pain- Coronary Disease- Heart Disease-…
Infections
01 Jan 2013
Vitamin A Therapy for Tuberculosis
The study will determine whether a daily vitamin and mineral supplement (a multivitamin including Vitamin A) will improve health when added to standard chemotherapy for tuberculosis. This study will compare the effectiveness of the multivitamin in HIV infected and HIV uninfected patients. Official Title Adjunct Vitamin A Therapy for Tuberculosis…
Mental Health
01 Jan 2013
Vitamin E in Aging Persons With Down Syndrome
The goal of this study is to determine the safety and efficacy of the administration of vitamin E, which has been shown to delay the progression of Alzheimer’s disease, in slowing the rate of cognitive/functional decline in older persons with Down syndrome. Official Title Multicenter Vitamin E Trial in Aging…
Mental Health
01 Jan 2013
Molecular Genetics of Schizophrenia
This study will orgnaize and release previously-obtained data from a DNA collection used to search for schizophrenia-related genes. The data will be made available to the scientific community for genetic studies of schizophrenia and related disorders. Official Title Conditions – Schizophrenia Study Type Observational Study Design Natural History…
Heart
01 Jan 2013
Abciximab (ReoPro) in Acute Ischemic Stroke
Multinational, Multicenter, Randomized, Double-blind, Placebo-controlled trial to evaluate efficacy and safety of Abciximab in Acute Ischemic Stroke onset within 6 hour time window and subjects who wake from sleep with stroke symptoms, and in whom the planned treatment initiation is within 3 hours of awakening. Multinational, Multicenter, Randomized, Double-blind, Placebo-controlled…
Chronic Pain
01 Jan 2013
Flecainide in Treating Patients With Chronic Neuropathic Pain
RATIONALE: Flecainide therapy may help patients with neuropathic pain live more comfortably. Official Title Phase II Study of Flecainide for the Treatment of Chronic Neuropathic Pain Conditions – Pain Study Type Interventional Study Design Treatment Further Details OBJECTIVES:Investigate the effectiveness of flecainide in the management of neuropathic pain. OUTLINE: Patients…