Evaluation of Patients with Known or Suspected Heart Disease

In this study researchers will admit and evaluate patients with known or suspected heart disease referred to the Cardiology Branch of the National Heart, Lung, and Blood Institute (NHLBI).

Official Title

Evaluation of Patients with Known or Suspected Heart Disease (Screening Protocol)

Conditions

– Chest Pain- Coronary Disease- Heart Disease- Hypertrophic Cardiomyopathy- Syndrome X

Study Type

Observational

Study Design

Screening

Further Details

Patients participating in this study will undergo a general medical evaluation, including blood tests, urine, examination, chest x-ray and electrocardiogram (EKG). In addition, patients may be asked to have an echocardiogram (ultrasound scan of the heart) and to perform an exercise stress test. These tests are designed to assess the types and causes of patient’s heart diseases and to determine if they can participate in other, specific research studies. The principal mission of the NIH is the conduct of research that elucidates biological mechanisms, pathogenesis, and treatment of disease. Patients with known or suspected cardiovascular diseases are referred to NHLBI cardiologists for consideration of participation in clinical research protocols. However, eligibility for participation is often uncertain from referral information or even after an outpatient evaluation. The purpose of this protocol is to permit inpatient evaluation of patients for whom participation in clinical research protocols is under consideration in order to determine protocol eligibility by means of conventional laboratory and cardiovascular testing.

Study Start

Eligibility & Criteria

Genders Eligible for Study: Both Criteria INCLUSION CRITERIA:The following is a representative list of the types of patient presentations and potential diagnoses eligible for this protocol:1. Coronary artery disease with effort or rest angina or inducible myocardial ischemia as determined by noninvasive testing.2. Cardiomyopathies, including restrictive, congestive, and hypertrophic phenotypes.3. Peripheral artery disease with intermittent claudication or limb-threatening ischemia.4. Renovascular disease with uncontrolled hypertension, intermittent pulmonary edema, or evidence of ischemic nephropathy.5. Upper extremity peripheral artery disease.6. Symptomatic supraventricular and ventricular arrhythmias.EXCLUSION CRITERIA:Pregnancy, for those patients who require catheterization-based diagnostics.Inability to provide informed consent.

Total Enrolment

9999

Contact Details

[1] National Heart, Lung and Blood Institute (NHLBI), 9000 Rockville Pike, Bethesda, Maryland, 20892, United States