Neurology
01 Jan 2013
Minocycline in Patients with Huntington’s Disease
This is a study to determine whether treatment with minocycline is safe and tolerable in patients with Huntington’s disease (HD) and whether minocycline reduces symptoms of HD in these patients. Official Title Conditions – Huntington’s Disease Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo Control, Safety/Efficacy Study Further…
Heart
01 Jan 2013
Home Automatic External Defibrillator Trial — HAT
To compare home use of an automatic external defibrillator to the local emergency medical system in survivors of a heart attack. To compare home use of an automatic external defibrillator to the local emergency medical system in survivors of a heart attack.Condition: – Cardiovascular Diseases- Myocardial Infarction- Heart Diseases- Death,…
Heart
01 Jan 2013
Oral Enoximone vs. Placebo in Advanced Chronic Heart Failure Subjects
To determine if low-dose enoximone therapy is an effective treatment for advanced chronic heart failure. Official Title ESSENTIAL Protocol No. My-021 and Protocol No. My-026, each titled: A Phase III, Randomized, Double-Blind, Multicenter, Parallel Group, Placebo-Controlled Study of Oral Enoximone vs. Placebo in Advanced Chronic Heart Failure Subjects Conditions…
Heart
01 Jan 2013
Healthy Heart Amputation Rehabilitation Treatment (H.A.R.T)
In the VA, we are achieving progress in decreasing amputation rates through early identification and multidisciplinary treatment of patients at risk for limb loss. Despite these accomplishments, however, clinical outcomes post-amputation, especially for PVD patients, have changed little because of patients’ poor cardiovascular condition complicated by the injurious consequences of…
Heart
01 Jan 2013
Periodontitis and Cardiovascular Events or
The purpose of this study is to determine if treating periodontal infections (gum problems) will lead to fewer heart problems in patients at high risk for cardiovascular disease. Official Title Periodontal Intervention for Cardiac Events: A Pilot Trial Conditions – Cardiovascular Disease- Coronary Heart Disease- Myocardial Infarction- Cerebrovascular Accident…
Cancer
01 Jan 2013
Surgery in Treating Children With Neuroblastoma
RATIONALE: Surgery alone may be effective in treating children with neuroblastoma. PURPOSE: Phase III trial to study the effectiveness of surgery alone in treating children who have neuroblastoma. Official Title Phase III Study of Primary Surgical Therapy in Children With Low-Risk Neuroblastoma Conditions – localized resectable neuroblastoma- stage 4S neuroblastoma…
Mental Health
01 Jan 2013
Duloxetine vs. active comparator in the treatment of patients with depression
How duloxetine compares to a medication currently available for the treatment of patients diagnosed with depression. Official Title Conditions – Depression Study Type Interventional Study Design Treatment Further Details Study Start Eligibility & Criteria Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both Criteria…
Mental Health
01 Jan 2013
Therapeutic Processes and Treatment Outcome in Adolescents with Anxiety Disorders
The purpose of this study is to examine the relationship between different aspects of cognitive behavior therapy (CBT) and treatment outcome. Official Title Process as a Predictor of Outcomes in CBT for Youth Conditions – Anxiety Disorders Study Type Interventional Study Design Treatment, Non-Randomized, Open Label, Active Control, Single…
Neurology
01 Jan 2013
Assessment of Chronic Guillain-Barre Syndrome Improvement with Use of 4-aminopyridine
In developed countries, Guillain-Barre Syndrome (GBS) is the most common cause of acute neuromuscular paralysis, afflicting about 5,000 persons annually in the United States. Over 20% of GBS patients have permanent residual motor deficits that affect their activities of daily living. The goal of this study is to assess the…
