Mental Health
01 Jan 2013
PUFA Augmentation in Treatment of Major Depression
The purpose of this study is to determine if omega-3 fatty acid EPA will enhance and speed up response to antidepressant therapy with Celexa (Citalopram) in people suffering from Major Depressive Disorder. All patients will receive Celexa, 50% will receive EPA, 50% placebo EPA. The purpose of this study is…
Heart
01 Jan 2013
EVEREST: Efficacy of Vasopressin antagonism in hEart failuRE: outcome Study with Tolvaptan
The purpose of this study is to compare the effectiveness of tolvaptan or placebo in adults with worsening congestive heart failure (CHF). The purpose of this study is to compare the effectiveness of tolvaptan or placebo in adults with worsening congestive heart failure (CHF). Condition: – Congestive Heart FailureStudy Type:…
Neurology
01 Jan 2013
Prevention of Alzheimer’s Disease by Vitamin E and Selenium (PREADVISE)
The Prevention of Alzheimer’s Disease by Vitamin E and Selenium (PREADVISE) prevention trial is an important addition to the Selenium and Vitamin E Cancer Prevention Trial (SELECT). As a prevention trial, PREADVISE is trying to find out if taking selenium and/or Vitamin E supplements can help to prevent memory loss…
Lungs
01 Jan 2013
Inhaled NO in Prevention of Chronic Lung Disease
Purpose To test the hypothesis that low-dose inhaled nitric oxide administered to preterm infants who continue to require mechanical ventilation at 14 days of age will reduce the incidence of chronic lung disease. Purpose To test the hypothesis that low-dose inhaled nitric oxide administered to preterm infants who continue…
Blood
01 Jan 2013
BEAM Trial
Purpose As many more premature infants survive, the numbers of these infants with health problems also has increased. The rate of cerebral palsy in extremely premature infants is approximately 20%. Magnesium sulfate, the most commonly used drug in the US used to stop premature labor may prevent CP. This…
Lungs
01 Jan 2013
Efficacy of QVAR vs Flovent Diskus on Small Airways in Poorly Controlled Asthmatic Adolescents/Adult Patients
Purpose The primary objective of this study is to evaluate the effect of Beclomethasone dipropionate HFA on small airways compared to Fluticasone propionate powder for inhalation administered twice daily to poorly controlled asthmatics. Purpose The primary objective of this study is to evaluate the effect of Beclomethasone dipropionate HFA…
Lungs
01 Jan 2013
The Genetics of Environmental Asthma
Purpose In this project, we hypothesize that polymorphisms of genes expressed by the airway epithelia in asthmatics following specific airway challenges predispose individuals to the development of asthma. To test this hypothesis, we plan to identify the genes that are differentially expressed by airway epithelial cells following challenge with…
Chronic Pain
01 Jan 2013
Evaluating Therapeutic Massage for Chronic Neck Pain
Purpose This study will provide the basis for a full-scale trial to evaluate the effectiveness and safety of therapeutic massage for chronic neck pain (CNP). The study will involve two phases: Phase I includes the development of massage and control protocols and the development of appropriate inclusion and exclusion…
Bone
01 Jan 2013
Look AHEAD
Purpose The Look AHEAD study is a multicenter, randomized clinical trial to examine the long-term effects of a lifestyle intervention designed to achieve and maintain weight loss. The study will investigate the effects of the intervention on heart attacks, stroke and cardiovascular-related death in individuals with type 2 diabetes…
