Heart
01 Jan 2013
Clinical Trial of Dietary Protein on Blood Pressure
Purpose To examine the effect of dietary protein supplementation on blood pressure. Official Title Conditions – Cardiovascular Diseases- Hypertension- Heart Diseases Study Type Interventional Study Design Prevention, Randomized, Double-Blind, Crossover Assignment Further Details BACKGROUND: At least 50 million adult Americans have hypertension, one of the most important modifiable…
Blood
01 Jan 2013
Aggressive vs. conservative red blood cell transfusion therapy in surgical patients with Cardiovascular Disease
Purpose: To compare aggressive with conservative red blood cell transfusion therapy in surgical patients with cardiovascular disease. Official Title Conditions – Anemia- Blood Disease- Blood Transfusion- Cardiovascular Diseases- Heart Diseases- Myocardial Infarction- Thromboembolism- Pneumonia- Cerebrovascular Accident Study Type Interventional Study Design Preventional, Randomised. Further Details BACKGROUND: Red blood cell…
Heart
01 Jan 2013
Effect of B blockade on haemodynamics and brain natriuretic peptide (BNP)
The aim of the study is to test the effects of Atenolol, Pindolol and Nebivolol on central blood pressure and augmentation index. Studies of normotensive and hypertensive individuals have confirmed that pulse pressure is a better predictor of cardiovascular events than mean pressure in older adults. Official Title Conditions Study…
Heart
01 Jan 2013
Perioperative stress response in infants undergoing cardiac surgery: a comparison of three alfentanil dosage regimens
Perioperative stress response in infants undergoing cardiac surgery: a comparison of three alfentanil dosage regimens Official Title Conditions Study Type Study Design Further Details What is the smallest dose of alfentanil that minimises neuro-hormonal stress response in infants undergoing cardiac surgery? 90 infants aged less than 1 year undergoing palliative…
Heart
01 Jan 2013
Predictors of Response to Cardiac Resynchronization Therapy
Predictors of Response to Cardiac Resynchronization Therapy. Official Title Conditions Study Type Study Design Further Details This important study will use echocardiograms to learn how to better predict heart failure patients who will have a positive response to biventricular pacing therapy. As this technology advances, it will be important to…
Heart
01 Jan 2013
(AFast) Atrial Fibrillation Suppression Trial
Suppression of Atrial Fibrillation in Patients without a Bradycardia Indication for Pacing. Official Title Conditions Study Type Study Design Further Details This trial will offer patients, who have atrial fibrillation without bradycardia, the option of a pacemaker to control their irregular heartbeats. For those patients whose irregular rhythms cannot be…
Heart
01 Jan 2013
EPILOG
Blockade of the platelet glycoprotein IIb/IIIa receptor with abciximab (a monoclonal-antibody Fab fragment directed against the receptor) has been shown to diminish ischemic complications among patients undergoing high-risk coronary angioplasty or directional atherectomy but increases bleeding complications. The widespread applicability of this treatment is unknown, particularly in view of the…
Heart
01 Jan 2013
STOPAMI-2
Patients with acute myocardial infarction might benefit from the addition of glycoprotein IIb/IIIa inhibitors to fibrinolytic or mechanical reperfusion strategies. We compared two strategies, stenting and fibrinolysis, both combined with abciximab, in terms of their ability to salvage myocardium in patients with acute myocardial infarction. Patients with acute myocardial infarction…
Heart
01 Jan 2013
STOPAMI
Prevention of myocardial damage is the main goal of all reperfusion therapies in patients with acute myocardial infarction. The relative efficacy of various reperfusion strategies is under intensive investigation. We assessed whether coronary stenting combined with the blockade of platelet glycoprotein IIb/IIIa receptors produces a greater degree of myocardial salvage…
