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Biological Markers in Parkinson’s Disease

Biological Markers in Parkinson’s Disease

This study will identify abnormalities of a protein called alpha synuclein that is found in the brain of patients with…

01 Jan 2013

Positron Emission Tomography to Measure Pain and Pain Control

This study will examine how the brain processes pain signals and how the different parts of the brain work with…

01 Jan 2013

Suppression of Ovarian Function Plus Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

RATIONALE: Estrogen can stimulate the growth of breast tumor cells. Ovarian function suppression combined with hormone therapy using tamoxifen or…

01 Jan 2013

Combination Chemotherapy With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin’s Lymphoma

Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal…

01 Jan 2013

Trial of PI-88 with Docetaxel in Advanced Non-Small-Cell Lung Cancer (NSCLC)

PI-88 is a new experimental drug that inhibits tumour growth by reducing the formation of new blood vessels into tumours.

01 Jan 2013

Pegvisomant and Sandostatin LAR Combination Study

To compare the safety and tolerability of combination therapy with Sandostatin LAR plus Pegvisomant to that of Sandostatin LAR alone…

01 Jan 2013

Bevacizumab to Treat Inflammatory Breast Cancer

This study will evaluate the effectiveness of the drug bevacizumab, in combination with doxorubicin and docetaxel, in improving survival of…

01 Jan 2013

A Dose-Escalation Vaccine Trial In HER2-Overexpressing Patients With High-Risk Breast Cancer

A Dose-Escalation Vaccine Trial In HER2-Overexpressing Patients With High-Risk Breast Cancer

This trial will test how safe this vaccine is. It also tests whether its introduction induces an immune response by…

01 Jan 2013

Bexarotene in Preventing Breast Cancer in Women at Genetic Risk

RATIONALE: Chemoprevention therapy uses certain drugs to try to prevent the development or recurrence of cancer. It is not yet…

01 Jan 2013