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Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

OBJECTIVES: I. Determine whether there is prompt engraftment after autologous peripheral blood stem cell transplantation using filgrastim (G-CSF) mobilization in…

01 Jan 2013

Study of SU011248 in Patients with Neuroendocrine Tumors

The primary objective of the study is to determine the efficacy and safety of SU011248 as a treatment for patients…

01 Jan 2013

Study of SU011248 in Patients with Metastatic Non-Small Cell Lung Cancer

Study of SU011248 in Patients with Metastatic Non-Small Cell Lung Cancer

The purpose of this study is to test whether SU011248 has activity and is safe in patients with metastatic non-small…

01 Jan 2013

FOLFOX4 in Patients with Normal and Abnormal Renal Function

This trial is a phase II study of patients with advanced gastrointestinal (GI) malignancies who will be assigned to one…

01 Jan 2013

SR34006 Compared to Placebo in Patients who have Completed 6 Months of Treatment for Symptomatic Pulmonary Embolism or Deep Vein Thrombosis

Patients diagnosed with pulmonary embolism (blood clot in the lung) or deep vein thrombosis (blood clot in a leg vein)…

01 Jan 2013

Maintenance ZD1839 (IRESSA®) Following Completion of Front Line, Platinum-Based, Double Chemotherapy in Subjects with Advanced or Metastatic Non-Small Cell Lung Cancer

Maintenance ZD1839 (IRESSA®) Following Completion of Front Line, Platinum-Based, Double Chemotherapy in Subjects with Advanced or Metastatic Non-Small Cell Lung Cancer

In this Phase IIIb, randomized, double-blind, maintenance study, 300 subjects with advanced or metastatic Non-Small Cell Lung Cancer (NSCLC) (Stage…

01 Jan 2013

Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT)

Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT)

To evaluate the effectiveness of aldosterone antagonist therapy in reducing all cause mortality in patients who have heart failure with…

01 Jan 2013

Prevention of cognitive decline in Alzheimer’s disease by ingested interferon alpha

Prevention of cognitive decline in Alzheimer’s disease by ingested interferon alpha

In this phase I-II parallel design, randomized, double-blind clinical trial we will determine if 3,000 or 30,000 units ingested hrIFN-a…

01 Jan 2013

Gemcitabine/Oxaliplatin (GEMOX) vs Carboplatin/Paclitaxel (CP) in Non-small Cell Lung Cancer (NSCLC)

The purpose of this study is to compare combination treatment of gemcitabine + oxaliplatin (GEMOX) with carboplatin + paclitaxel (CP)…

01 Jan 2013