Lungs
01 Jan 2013
Sarcoid Genetic Analysis (SAGA)
To identify sarcoidosis susceptibility genes and to determine how these genes and environmental risk factors interact to cause sarcoidosis. Official Title Conditions – Lung Diseases- Sarcoidosis Study Type Observational Study Design Natural History, Defined Population Further Details BACKGROUND: Sarcoidosis is a rare systemic granulomatous disease that mainly affects…
Mental Health
01 Jan 2013
Behavioral Treatment, Drug Treatment, and Combined Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to determine the effectiveness of behavioral treatment, drug treatment, and combined treatment for children with Attention Deficit Hyperactivity Disorder (ADHD). This study will also examine the interactions between different levels of behavioral and drug treatments. Official Title ADHD Treatment: Comparative and Combined Dosage Effects…
Cancer
01 Jan 2013
Vaccine Treatment for Advanced Melanoma
This study will examine the safety and effectiveness of treatment with an experimental vaccine for melanoma, a type of cancer that arises from pigmented areas, usually of the skin. Melanoma tumors produce a protein called gp100. Vaccination with this protein may boost the immune system’s fight against the cancer. The…
Heart
01 Jan 2013
Qigong Therapy For Heart Device Patients
The goal of this study is to improve the overall physical health and quality of life of patients attached to mechanical heart devices while awaiting heart transplantation. Qigong, an ancient Chinese exercise that involves active participation of the individual in the form of meditation, breathing exercises and simple physical movements,…
Infections
01 Jan 2013
Investigating Severe Acute Respiratory Syndrome (SARS)
Severe Acute Respiratory Syndrome (SARS) is a newly recognized illness that can be fatal. Official Title An Investigation of the Inflammatory Response in Severe Acute Respiratory Syndrome (SARS) Conditions -SARS Virus Study Type Observational Study Design Natural History Further Details The purpose of this study is to better understand SARS…
Blood
01 Jan 2013
Low-Dose Total-Body Irradiation, Fludarabine, and Alemtuzumab Followed By Allogeneic Stem Cell Transplantation in Treating Patients With Myeloproliferative Disorder or Myelodysplastic Syndrome
Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy and radiation therapy. Sometimes the transplanted cells reject the body’s normal tissues. Alemtuzumab may prevent this from happening. Official Title Phase II Study of Submyeloablative Conditioning Regimen Comprising Low-Dose Total Body Irradiation, Fludarabine,…
Blood
01 Jan 2013
Imatinib Mesylate in Treating Patients With Myelofibrosis
Imatinib mesylate may stop the growth of myelofibrosis by blocking certain enzymes necessary for cell growth. Official Title Phase II Study of Imatinib Mesylate in Patients With Myelofibrosis Conditions – Polycythemia Vera- chronic idiopathic myelofibrosis- Essential Thrombocythemia- Chronic Myelomonocytic Leukemia Study Type Interventional Study Design Treatment Further Details OBJECTIVES:Determine the…
Bone
01 Jan 2013
Shoe Insert Study
This trial will test shoe inserts for the treatment of knee osteoarthritis, the most common form of knee arthritis. Those with disease on the inner (medial) aspect of the knee will be studied. Official Title Randomized Trial of a Wedged Insole for Treatment of Osteoarthritis of the Knee Conditions –…
Bone
01 Jan 2013
Genetic Determinants of Ankylosing Spondylitis Severity
This study will explore how genes-units of heredity-may influence the severity of ankylosing spondylitis. It will examine whether some genes may cause people with ankylosing spondylitis to have more rapid fusion of the bones of the spine, more difficulty performing daily activities, or be more likely to need joint surgery.
