Research and Trials

Bone 01 Jan 2013

Vertebroplasty for the Treatment of Fractures Due to Osteoporosis

Vertebroplasty is a procedure used to stabilize broken vertebrae, the bones that form the spine. This study will evaluate the effectiveness of vertebroplasty for the treatment of fractures due to osteoporosis. Official Title Investigational Vertebroplasty Efficacy and Safety Trial (INVEST) Conditions – Spinal Fractures- Osteoporosis Study Type Interventional Study…
Bone 01 Jan 2013

Once Weekly Parathyroid Hormone for Osteoporosis

Daily parathyroid hormone (PTH) is approved by the FDA for the treatment of osteoporosis. This study will evaluate the safety and effectiveness of PTH when given once a week. Official Title PTH Once Weekly Research (POWR) Conditions – Osteopenia- Osteoporosis Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo…
Mental Health 01 Jan 2013

Ginkgo Biloba: Antidepressant-Induced Sexual Dysfunction

The purpose of this study is to provide the first empirical examination of the effects of Ginkgo biloba (GBE), sex therapy, and a combination of the two on subjective and physiological measures of sexual function in women who are experiencing sexual disorders secondary to antidepressants. Official Title Conditions – Hypoactive…
Bone 01 Jan 2013

Preventing Osteoporosis in Adolescent Girls

Physical activity in adolescents is an important part of bone health. Good bone health in adolescents can decrease the risk of osteoporosis. This study will evaluate a program designed to increase the level of physical activity in adolescent girls. Official Title Prevention of Osteoporosis Among Sedentary Adolescent Females Conditions –…
Neurology 01 Jan 2013

Brain Study of Patients with Frontal Lobe Dementia and Parkinsonian Disorders

The Cognitive Neuroscience Section of the National Institute of Neurological Disorders and Stroke proposes to continue its cross-sectional and longitudinal studies of cerebral metabolism in frontal lobe dementias and atypical basal ganglia disorders. These studies include repeated assessments of neuropsychological and brain anatomical and metabolic function in subjects with these…
Neurology 01 Jan 2013

Diagnosis and History Study of Patients with Different Neurological Conditions

The goal of this study is to diagnose and follow patients with disorders of movement control. Patients participating in this study will undergo routine laboratory tests and examinations in order to monitor their condition. Official Title Diagnosis and Natural History Protocol for Patients with Different Neurological Conditions Conditions – Nervous…
Bone 01 Jan 2013

Studies on Abnormal Bone from Patients with Polyostotic Fibrous Dysplasia and McCune Albright Syndrome

This study will investigate how a gene mutation (change in DNA) causes the abnormal bone in fibrous dysplasia-a condition in which areas of normal bone are replaced with a fibrous growth similar to a scar. The bone abnormalities in fibrous dysplasia can occur in a single bone (monostotic fibrous dysplasia),…
Bone 01 Jan 2013

Bone Mineral Density in Women with Major Depression

The purpose of this study is to examine calcium absorption and bone mineral density in women with depression. Research indicates that pre-menopausal women with depression have significantly lower bone mineral density (BMD) than pre-menopausal women without depression. Although the mechanisms of BMD loss are unclear, researchers believe that individuals with…
Bone 01 Jan 2013

Bone Regeneration Using Stromal Cells

This study will evaluate the possible use of bone marrow stromal cells-a type of cell related to bone and fibrous tissue-for jaw bone grafting. When a tooth is lost or removed, there is usually a gradual loss of bony tissue from the jawbone at the site of the missing tooth.