Neurology
01 Jan 2013
Study to Compare the Effect of Treatment With Carbidopa/Levodopa/Entacapone on the Quality of Life of Patients With Parkinson’s Disease.
This study examines the effect of treatment of levodopa/entacapone on quality of life, as measured by the Parkinson’s Disease-Questionnaire 8 (PDQ-8), in Parkinson’s disease patients with no or minimal, non-disabling motor fluctuations. Official Title A randomized, double-blind, parallel-group, multi-national study to compare the effect on quality of life of levodopa/carbidopa/entacapone…
Neurology
01 Jan 2013
Cooperative Huntington’s Observational Research Trial
The purpose of this study is to collect prospective data from individuals who are part of a Huntington Disease (HD) family, in order to relate phenotypes between individuals and families with each other and genetic factors in order to learn more about HD, develop potential treatments for HD, and to…
Mental Health
01 Jan 2013
Genetics of Obsessive-Compulsive Disorder
The purpose of this study is to identify genes that affect susceptibility to obsessive-compulsive disorder (OCD). By identifying genes that increase or decrease the risk of OCD, researchers can better understand how the condition develops and ultimately improve treatment for people with OCD. Official Title Genetics of Obsessive-Compulsive Disorder: A…
Mental Health
01 Jan 2013
A Study of Risperidone Long-Acting Injection Versus Oral Antipsychotics in Schizophrenia Patients With a History of Being Poorly Compliant With Taking Their Medication
The purpose of this study is to evaluate risperidone long-acting injection (an antipsychotic medication) versus oral antipsychotics in schizophrenia patients with a history of being poorly compliant with taking their medication. Official Title Pragmatic Randomized Trial of ‘Risperdal CONSTA’ (Risperidone) Versus Oral Atypical Antipsychotics in Poorly Adherent Subjects With Schizophrenia…
Mental Health
01 Jan 2013
Study Evaluating the Safety, Tolerability, and Efficacy of Lecozotan SR in Outpatients With Alzheimer’s Disease
The purpose of the study is to determine the safety, tolerability, and efficacy of 3 doses of lecozotan in combination with a cholinesterase inhibitor in patients with mild to moderate Alzheimer’s disease (AD). Official Title A 6-Month, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Safety, Tolerability, and Efficacy Study of 3 Doses of…
Mental Health
01 Jan 2013
Prospective Research in Memory Clinics (PRIME), a Disease Registry for Current Management of Treatment and Outcome in Patients With Dementia (or Alzheimer’s).
The purpose of the PRIME (Prospective Research in Memory Clinics) Study is to examine the current management and outcomes of patients with dementia. Approximately 4500 subjects will be enrolled in this disease registry across 12 sites in Australia. Clinical, treatment, health status and economic data will be acquired over 3…
Children's health
01 Jan 2013
Long-Term, Open Label Atomoxetine Study on Attention Deficit Hyperactivity Disorder
To learn about the safety and any side effects of atomoxetine when given to children and adolescents for about 5 years (long-term) and to learn whether atomoxetine can help children and adolescents with ADHD who take the drug for about 5 years (long-term). Official Title Long-Term, Open Label Safety Study…
Bone
01 Jan 2013
Study of Daily Pentoxifylline as a Rescue Treatment in Duchenne Muscular Dystrophy
The purpose of this study is to see if male children with Duchenne muscular dystrophy (DMD) have changes in strength when given the drug Pentoxifylline as a rescue treatment. A total of 64 subjects are expected to participate through all other centers of the Cooperative International Neuromuscular Research Group (CINRG)…
Heart
01 Jan 2013
Ancrod (Viprinex) for the Treatment of Acute, Ischemic Stroke
The primary purpose of this study is to determine whether a brief intravenous infusion of ancrod started within 6 hours of stroke onset improves functional outcome at 3 months. Official Title Study of Acute Viprinex for Emergency Stroke: A Randomized, Double-Blind, Placebo-Controlled Study of Ancrod (Viprinex) in Subjects Beginning Treatment…
