Endocrinology

Kale chips
Blood 20 Aug 2013

Kale chips

These crispy homemade chips are packed with flavour and nutrients. It’s amazing that just by drying kale, a delicious leafy green, you end up with…
Lymphatic System
Blood 27 Apr 2013

Lymphatic System

The lymphatic system the body's secondary circulatory system. Its functions are closely linked to the functions of the body's primary circulatory system, the blood circulation. Organs and cells of the lymphatic system play an integral role in supporting the immune system, which is a functional system consisting of cells (e.g. blood cells which fight infection) and molecules (e.g. antibodies which protect against particular diseases). Unlike other body systems the immune system has no organs.
Adolescent stress linked to severe adult mental illness
Children's health 29 Jan 2013

Adolescent stress linked to severe adult mental illness

Working with mice, Johns Hopkins researchers have established a link between elevated levels of a stress hormone in adolescence – a critical time for brain development – and genetic changes that, in young adulthood, cause severe mental illness in those predisposed to it. The findings, reported in the journal Science,…
CAROLINA: Cardiovascular Outcome Study of Linagliptin versus Glimepiride in Patients with Type 2 Diabetes
Heart 01 Jan 2013

CAROLINA: Cardiovascular Outcome Study of Linagliptin versus Glimepiride in Patients with Type 2 Diabetes

The aim of the study is to investigate the long-term impact on cardiovascular morbidity and mortality, relevant efficacy parameters (e.g., glycaemic parameters) and safety (e.g., weight and hypoglycaemia) of treatment with linagliptin in patients with type-2 diabetes at elevated cardiovascular risk receiving usual care, and compare outcome against glimepiride. Official…
Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques (IMPART)
Children's health 01 Jan 2013

Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques (IMPART)

This study is to compare the effects of high-fat overfeeding on metabolic risk factors in children born through assisted reproduction technologies (ART) versus children conceived naturally (controls). We will utilise state of the art measures to characterise the physiological, endocrine and molecular responses to high fat overfeeding. The investigators…
Hormones 01 Jan 2013

Vitamin D in Vietnamese Research Project

A current research project aims to build on the results of an earlier study which revealed that Vitamin D deficiency is as high as 88% (9 out of 10 people) in Vietnamese living in Melbourne. Research will now assess the effectiveness of Vitamin D supplements in the treatment of Graves’…
Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer
Cancer 01 Jan 2013

Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer

The purpose of this study is to determine if patients with metastatic prostate cancer who have not received chemotherapy live longer when treated with ipilimumab than those treated with a placebo. Official Title Randomized, Double-Blind, Phase 3 Trial to Compare the Efficacy of Ipilimumab vs Placebo in Asymptomatic or Minimally…
Hormones 01 Jan 2013

Effect of Growth Hormone on Insulin Signaling in Muscle Tissue

The purpose of this study is to examine the effects of a physiological bolus of growth hormone on insulin signaling pathways in muscle tissue in healthy lean men. Official Title The Effect of a Physiological Bolus of Growth Hormone (GH) on Insulin Signaling Pathways in Muscle Tissue From Healthy Adults…
Hormones 01 Jan 2013

Thyroxine Titration Study

The aim of the study is to examine the effects of fine titration of thyroxine dosage on symptoms of hypothyroidism, wellbeing and quality of life. The hypothesis is that symptoms of hypothyroidism, wellbeing and quality of life will be improved in thyroxine-treated subjects when serum thyrotropin (TSH) is suppressed and/or…