Cancer
01 Jan 2013
Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema
The purpose of this study is to assess the efficacy and safety of Icatibant, a bradykinin antagonist in the treatment of acute cutaneous and/or abdominal attacks in patients with hereditary angioedema (HAE). Official Title Randomised, Double Blind, Placebo-Controlled, Multicenter Study of a Subcutaneous Formulation of Icatibant for the Treatment of…
Research and Trials
01 Jan 2013
Evaluating the Effectiveness of Financial Incentives in Promoting Weight Loss Among Obese Individuals
Obesity is a major cause of premature aging and the second leading cause of preventable mortality in the United States, accounting for approximately 110,000 deaths per year. Financial incentives have been effective in modifying a number of health behaviours but they have rarely been applied to weight loss, and to…
Research and Trials
01 Jan 2013
LEAN Project: Weight Loss and Appetite Suppression
The primary aim is to examine whether the intake of PhosphoLEAN is effective in aiding a cohort of women in losing weight. Participants taking the supplement will have significantly greater improvement in study outcomes than those taking the placebo. Official Title The Effect of Soy Lecithin-Derived N-Oleoyl-Phosphatidyl-Ethanolamine (NOPE) and Green…
Research and Trials
01 Jan 2013
High Fat Diet II on Weight Loss (HFD)
To evaluate two different diets and their effects on weight loss and measurements of several risk factors for cardiovascular disease. One diet will be a high saturated fat diet (HSFD) and the other is a low saturated fat diet (LSFD) that limits fat but especially saturated fat as red meat.
Research and Trials
01 Jan 2013
Weight Loss Maintenance in Primary Care (PrimaryCare)
After a three month weight loss phase involving the use of meal replacements, participants are randomised into different weight loss maintenance conditions. Aim 1: To test the hypothesis that the meal replacement (MR) and reduced energy density eating (REDE) interventions, when added separately to the LEARN program, will produce superior…
Research and Trials
01 Jan 2013
Physical Activity Following Surgery Induced Weight Loss
The primary objective of this study will be to determine the effects of physical activity in patients during substantial surgery-induced weight loss. A randomised controlled physical activity intervention trial in a group of patients undergoing bariatric surgery for weight loss. The study will involve two sites with an active bariatric…
Joints
01 Jan 2013
Influence of Weight Loss or Exercise on Cartilage in Obese Knee Osteoarthritis Patients (CAROT)
Obesity and osteoarthritis (OA) co-exist in an increasing part of the population.The two diseases intertwine in several ways. The evolution in the population shows a tendency towards deterioration of both by increasing general age and weight. The two diseases share pathogenetic features and the development of one disease increases the…
Research and Trials
01 Jan 2013
Comparison of Two Workplace-Sponsored Obesity Prevention Programs (The WAY to Health Study)
Obesity has reached epidemic proportions in the United States with nearly 64% of American adults considered overweight or obese. Weight loss programs that take place at work have proven to be effective at promoting healthy lifestyles. The purpose of this study is to compare the effectiveness of a Web-based weight…
