Gastro
01 Jan 2013
Long-Term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)
Gastroesophageal reflux disease (GERD) is a medical condition affecting the stomach and oesophagus. GERD might occur when the lower oesophageal sphincter does not close properly and stomach contents leaks back (refluxes) into the oesophagus. GERD is one of the most common medical disorders, with estimates of up to 50% of…
Gastro
01 Jan 2013
Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass
It is estimated that up to 20% of patients who have Roux-en-Y Gastric Bypass (RYGB) surgery will not meet their weight loss goal, or may even regain some of the weight they initially lost. One possible explanation is that the opening between the stomach pouch and the intestine becomes stretched.
Gastro
01 Jan 2013
Foreshortened Oesophagus and Its Surgical Therapy (GERDSurgery)
The existence, diagnosis and treatment of short oesophagus is one of the controversies of the past which has recently re-emerged. The missed diagnosis of short oesophagus and the consequent inadequacy of treatment is one of the major causes of failure of antireflux surgery. Official Title Frequency, Predictors, Intraoperative Assessment and…
Children's health
01 Jan 2013
Safety and Immunogenicity of 2 Formulations of an Intramuscular A/H5N1 Pandemic Influenza Vaccine in Children
This is an open, randomised, multicentre clinical trial.Objectives:To describe the safety profiles during the 21 days following each primary and booster injection.To describe the immune response 21 days after each primary and booster injection of each formulation.To describe the antibody persistence after the first vaccination. Official Title Conditions Influenza…
Children's health
01 Jan 2013
Evaluation Of Valaciclovir In Patients With Chickenpox
This study will assess the safety and efficacy, and the pharmacokinetics of aciclovir and valaciclovir in children with chickenpox following oral administration of valaciclovir, for the purpose of seeking approval of valaciclovir HCl for the treatment of chickenpox. Official Title Clinical Evaluation of Valaciclovir Hydrochloride: 256U87 in Patients With Chickenpox…
Children's health
01 Jan 2013
Evaluation of a Combined Vaccine Against 4 Viral Childhood Diseases: Measles, Mumps, Rubella and Chickenpox.
A study to evaluate GlaxoSmithKline Biologicals’ live attenuated varicella vaccine and GlaxoSmithKline Biologicals’ combined measles-mumps-rubella-varicella vaccine in the prevention of varicella disease in children. Official Title Study in Healthy Children (<2 Years) to Evaluate the Safety & Efficacy of GSK Biologicals’ Live Attenuated Varicella Vaccine (Varilrix) & of GSK Biologicals’…
Bone
01 Jan 2013
Pamidronate to Treat Osteogenesis Imperfecta in Children
This study will evaluate the effect of pamidronate-a drug that decreases bone resorption (breakdown)-on osteogenesis imperfecta. This is a genetic disorder of collagen, the major protein in bone. The abnormal collagen causes weak bones, and children with severe osteogenesis imperfecta sustain many fractures throughout their lives. They also have growth…
Bone
01 Jan 2013
Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Haematologic Cancers or Other Diseases
Rationale:Listening to relaxing music during a bone marrow biopsy may be effective in reducing anxiety and pain.Purpose:This randomised clinical trial is studying how well music works in reducing anxiety and pain in adult patients undergoing bone marrow biopsy for haematologic cancers or other diseases. Official Title Use of Music to…
Bone
01 Jan 2013
Cytokine Gene Polymorphisms in Bone Marrow Failure
This study will examine whether cytokine gene polymorphisms affect the progression or response to therapy of bone marrow failure disorders. Cytokine genes instruct cells to produce proteins called cytokines that influence immune system response. As with many genes, the cytokine genes differ slightly from person to person. These differences are…
