The primary aim is to examine whether the intake of PhosphoLEAN is effective in aiding a cohort of women in losing weight. Participants taking the supplement will have significantly greater improvement in study outcomes than those taking the placebo.

Official Title

The Effect of Soy Lecithin-Derived N-Oleoyl-Phosphatidyl-Ethanolamine (NOPE) and Green Tea-Derived Epigallocatechin Gallate (EGCG) on Indices of Weight Loss and Appetite Suppression


  • Weight Loss

Study Type


Study Design

Treatment, Randomised, Double-Blind, Placebo Control, Single Group Assignment, Safety/Efficacy Study

Further Details

Primary Outcome Measures:

  • Weight Loss
  • Appetite Suppression

Study Start

April 2005

Eligibility & Criteria


  • Ages Eligible for Study: 30 years to 45 years
  • Genders Eligible for Study: Female
  • Accepts Healthy Volunteers: Yes


Inclusion Criteria:

  • 30-45 years, women, overweight or obese class I, premenopausal, maintain current diet and exercise regimen

Exclusion Criteria:

  • Pregnant or planning to become pregnant
  • Currently has or history of
    • Cancer
    • Heart disease
    • Anaemia
    • Diabetes
    • Depression

Total Enrolment


Contact Details

Please refer to this study by its identifier: NCT00153790


The Cooper Institute      
Dallas, Texas, United States, 75230

Sponsors and Collaborators

The Cooper Institute

Chemi Nutra


Principal Investigator:

Conrad Earnest, PhD 
The Cooper Institute