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Children's health 01 Jan 2013

Dust Mite Allergen Reduction Study

This study will determine whether use of an in-home test kit results in decreased dust mite allergen levels in homes of children who are sensitive or allergic to dust mites. Dust mite allergens come from dust mites - microscopic spider-like animals that feed on house dust. Dust mites are common anywhere there is dust, such as in carpeting and beds. Some people are allergic to dust mite allergens and may develop asthma from living near them. Official TitleDust Mite Allergen Reduction Study
Research and Trials 01 Jan 2013

PRIDE – Prograf Investigation of Diet and Exercise. A Pilot Trial of the Effect of Dietary and Exercise Intervention in Patients Who Have Received a Renal Transplant on Tacrolimus (Prograf)

The purpose of this trial is to investigate whether a combined dietary and exercise intervention, added to standard care, reduces the expected frequency of insulin resistance in kidney transplant recipients on tacrolimus. Official Title A Pilot Trial of the Effect of Dietary and Exercise Intervention on Insulin Resistance and Metabolic…
Gastro 01 Jan 2013

The Rabeprazole and Esomeprazole Reflux Assessment Trial (TREAT)

The primary objective of this study is to compare, the number of patients with heartburn and regurgitation symptom resolution after treatment with either rabeprazole 20 mg, esomeprazole 20 mg or esomeprazole 40 mg. Official Title A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn…
Research and Trials 01 Jan 2013

Audit of the Effect of Changing From Intravenous to Subcutaneous Administration of Erythropoeisis Stimulating Agents in Haemodialysis Patients

The purpose of this study is to audit the effects of changing all haemodialysis patients from intravenous to subcutaneous administration of ESA’s, to ensure that a cost-saving is achieved and that this does not occur at the expense of anaemia control. The dose changes will occur according to usual clinical…
Children's health 01 Jan 2013

Can a Physical Activity Skill Development and Parent-Centered Dietary Intervention Help Combat Child Obesity?

The purpose of this study, and its original contribution to research, is to determine the impact of a physical activity skill development and parent centered family weight management program on the weight, cardiovascular health, physical activity, dietary intake and sedentary behaviors of overweight and obese children. Official Title Effect of…
Research and Trials 01 Jan 2013

Cognitive Behavioural Therapy for Obesity

The purpose of this study is to evaluate the effectiveness of a cognitive behavioural treatment (CBT) designed to help obese patients lose weight and to maintain their weight losses over time. It is hypothesized that CBT will result in greater sustained weight loss compared to a standard behavioural weight loss…
Gastro 01 Jan 2013

A Study to Evaluate the Efficacy and Safety of CCX282-B in Subjects With Moderate to Severe Crohn’s Disease

The purpose of this study is to determine whether CCX282-B is effective in treating patients with moderate to severe Crohn’s Disease. Official Title A Multinational, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of CCX282-B in Subjects With Moderate to Severe Crohn’s Disease Conditions Crohn’s Disease…
Cancer 01 Jan 2013

A Single Arm Trial of Oxaliplatin and 5FU With Concurrent Radiation in Patients With Metastatic Rectal Cancer

This trial is a single-arm study for patients presenting with both local and metastatic adenocarcinoma of rectum. The aims of the trial are (1) to determine the tolerability rate, and (2) to determine toxicity rates, pelvic and distant response rates in patients with locally advanced rectal cancer in the presence…
Cancer 01 Jan 2013

Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps

This randomized phase III trial is studying celecoxib to see how well it works compared to a placebo in preventing the development of adenomatous colorectal polyps in patients who have had at least one polyp removed. Official Title Prevention of Sporadic Colorectal Adenomas With Celecoxib (APC) Conditions Colorectal Cancer Study…