Cancer
01 Jan 2013
Trial for First-Line Treatment of Colorectal Cancer
In this study, patients will receive either ALIMTA (pemetrexed) plus irinotecan or 5-fluorouracil (5-FU), leucovorin, and irinotecan. The purposes of this study are to determine: How ALIMTA plus irinotecan compares with 5-FU, leucovorin, and irinotecan in terms of efficacy. The safety of ALIMTA plus irinotecan and any side…
Gastro
01 Jan 2013
Nutritional Restriction and Activity Thermogenesis
These studies will provide us with enormous insight regarding how obese patients adapt energetically during negative energy balance. We will gain fundamental information regarding the metabolic implications of combining food restriction with a walking program compatible to that advocated by statutory agencies. These studies will lead to improved understanding of…
Bone
01 Jan 2013
Clinically Important Changes in Rheumatoid Arthritis
This study will explore how patients with rheumatoid arthritis evaluate, or rate, symptom improvements. Physicians generally evaluate patients’ health and treatment benefits based on laboratory measures, such as the number of tender or swollen joints, duration of morning stiffness, grip strength, pain severity and others. Less attention is given to…
Bone
01 Jan 2013
dnaJ Peptide for Relieving Rheumatoid Arthritis
A small protein called dnaJ peptide may help people with rheumatoid arthritis (RA) by preventing their immune system cells from attacking their own tissues. The purpose of this study is to determine if small amounts of dnaJ peptide can “re-educate” immune cells in people with RA so that the cells…
Bone
01 Jan 2013
Bone Response to Soy Isoflavones in Women
This study will provide valuable data on whether soy isoflavones impact bone loss in postmenopausal women. The study will help clarify potential mechanisms and contribute to our understanding of isoflavones as an alternative to traditional hormone therapy. Official Title Conditions – Osteopenia- Osteoporosis Study Type Interventional Study Design Prevention,…
Bone
01 Jan 2013
EVA: Evista Alendronate Comparison
The purpose of this study is to determine how treatment with raloxifene compares to treatment with alendronate in postmenopausal women with osteoporosis on the chance of experiencing fractures The purpose of this study is to determine how treatment with raloxifene compares to treatment with alendronate in postmenopausal women with osteoporosis…
Bone
01 Jan 2013
Nitroglycerin Ointment for Preventing Bone Loss in Postmenopausal Women
Osteopenia and osteoporosis cause thinning of bone tissue and loss of bone density over time. The purpose of this study is to determine the safety and effectiveness of nitroglycerin ointment for the treatment of osteopenia in postmenopausal women. Official Title Prevention of Postmenopausal Bone Loss with Nitric Oxide Conditions –…
Bone
01 Jan 2013
Vertebroplasty for the Treatment of Fractures Due to Osteoporosis
Vertebroplasty is a procedure used to stabilize broken vertebrae, the bones that form the spine. This study will evaluate the effectiveness of vertebroplasty for the treatment of fractures due to osteoporosis. Official Title Investigational Vertebroplasty Efficacy and Safety Trial (INVEST) Conditions – Spinal Fractures- Osteoporosis Study Type Interventional Study…
Bone
01 Jan 2013
Once Weekly Parathyroid Hormone for Osteoporosis
Daily parathyroid hormone (PTH) is approved by the FDA for the treatment of osteoporosis. This study will evaluate the safety and effectiveness of PTH when given once a week. Official Title PTH Once Weekly Research (POWR) Conditions – Osteopenia- Osteoporosis Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo…
