Cancer
01 Jan 2013
Vaccine Treatment for Advanced Melanoma
This study will examine the safety and effectiveness of treatment with an experimental vaccine for melanoma, a type of cancer that arises from pigmented areas, usually of the skin. Melanoma tumors produce a protein called gp100. Vaccination with this protein may boost the immune system’s fight against the cancer. The…
Blood
01 Jan 2013
Imatinib Mesylate in Treating Patients With Myelofibrosis
Imatinib mesylate may stop the growth of myelofibrosis by blocking certain enzymes necessary for cell growth. Official Title Phase II Study of Imatinib Mesylate in Patients With Myelofibrosis Conditions – Polycythemia Vera- chronic idiopathic myelofibrosis- Essential Thrombocythemia- Chronic Myelomonocytic Leukemia Study Type Interventional Study Design Treatment Further Details OBJECTIVES:Determine the…
Bone
01 Jan 2013
Shoe Insert Study
This trial will test shoe inserts for the treatment of knee osteoarthritis, the most common form of knee arthritis. Those with disease on the inner (medial) aspect of the knee will be studied. Official Title Randomized Trial of a Wedged Insole for Treatment of Osteoarthritis of the Knee Conditions –…
Bone
01 Jan 2013
Genetic Determinants of Ankylosing Spondylitis Severity
This study will explore how genes-units of heredity-may influence the severity of ankylosing spondylitis. It will examine whether some genes may cause people with ankylosing spondylitis to have more rapid fusion of the bones of the spine, more difficulty performing daily activities, or be more likely to need joint surgery.
Bone
01 Jan 2013
Study of Arthritis and Related Conditions
The purpose of this study is to learn more about the causes of rheumatoid arthritis, juvenile rheumatoid arthritis and related conditions and the course of these diseases. Patients in this study will not receive treatment, but may be offered participation in a treatment protocol if an appropriate study is available.
Bone
01 Jan 2013
Literacy in Arthritis Management
This study will test a new patient education program designed for people who do not read well. It will also look at how poor reading skills affect a person’s health and how people who do not read well learn best. We will randomly assign patients who have a rheumatic condition…
Gastro
01 Jan 2013
Peptic Ulcer Hemorrhage Study
To evaluate the efficacy and safety of intravenous pantoprazole in the prevention of rebleeding in patients with bleeding peptic ulcer disease after successful endoscopic hemostatic therapy. Official Title An efficacy and safety study of intravenous pantoprazole in the prevention of recurrent peptic ulcer bleeding after successful hemostasis. Conditions – Peptic…
Infections
01 Jan 2013
Intrathecal Gemcitibine to Treat Neoplastic Meningitis
Gemcitabine is an investigational drug for treatment of neoplastic meningitis (cancer that has spread to the lining of the brain and spinal cord). The purposes of this study are: to determine the highest dose of gemcitabine, an anti-cancer drug, that can safely be given directly into the spinal fluid…
Infections
01 Jan 2013
Experimental Ebola Vaccine Trial
This study will test the safety of an experimental vaccine developed to protect against Ebola virus infection and to determine if the vaccine induces an immune response to the virus. The Ebola virus causes a disease called Ebola hemorrhagic fever. Symptoms begin with fever and muscle aches and progress to…
