Infections
01 Jan 2013
Assessment of valganciclovir in neonates with CMV
Primary: -To determine the pharmacokinetics of ganciclovir following administration of oral valganciclovir syrup in neonates and young infants with symptomatic congenital CMV disease -To identify a dose of valganciclovir to provide comparable ganciclovir plasma concentrations in neonates and young infants with symptomatic congenital CMV disease. Secondary: -To evaluate…
Gastro
01 Jan 2013
Barrett’s Esophagus Early Detection Study
The incidence rate for esophageal adenocarcinoma (EAC) has risen 10% per year over the past two decades and is the most rapidly increasing cancer in the U.S. Potential reasons for this increase include obesity and gastroesophageal reflux disease (GERD). Prevention strategies to date have focused on early detection. Barrett’s esophagus…
Gastro
01 Jan 2013
Peg-Intron for Prevention of Disease Progression in Chronic Hepatitis C Patients with Cirrhosis (failing with Interferon plus Ribavirin treatment)
The objective of the study is to evaluate the safety and efficacy of PEG-Intron vs. no treatment for the prevention of disease progression in adult subjects with compensated cirrhosis secondary to chronic hepatitis C, who failed to respond to therapy with an a interferon plus ribavirin. Official Title Peg-Intron for…
Cancer
01 Jan 2013
Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using either tamoxifen or anastrozole may fight breast cancer by blocking the uptake of estrogen. It is not yet known whether tamoxifen is more effective than anastrozole in preventing breast cancer after surgery for ductal carcinoma in situ.
Gastro
01 Jan 2013
Genetic Linkage Study for Hereditary Pancreatitis
OBJECTIVES: Establish linkage in families with hereditary pancreatitis between the phenotype and a chromosomal locus (loci) that contains the responsible gene. Official Title – Pancreatitis Conditions Study Type Observational Study Design Natural History Further Details PROTOCOL OUTLINE: This is a genetics study. Blood samples are collected from patients…
Gastro
01 Jan 2013
The Safety and Effectiveness of Low and High Carbohydrate Diets
This study will compare the safety and the effectiveness of a low carbohydrate diet (Atkins diet) with a high carbohydrate diet (conventional USDA diet). Official Title The Safety and Efficacy of Low and High Carbohydrate Diets Conditions – Obesity Study Type Interventional Study Design Treatment, Randomized, Open Label, Uncontrolled,…
Gastro
01 Jan 2013
FFA Metabolism in Different Types of Human Obesity
We will give intravenous fat molecules to help us understand how the fat that is released from peoples fat cells is used. This will be done when people are eating, not eating and walking. Official Title Conditions – Obesity Study Type Observational Study Design Natural History, Cross-Sectional, Defined Population, Prospective…
Gastro
01 Jan 2013
Supplemental Calcium in Overweight People
This study will examine the health effects of calcium supplements in overweight adults. Overweight adults often eat a diet low in calcium. Some studies have found low calcium intake in people who have some of the medical problems often seen in overweight adults. This study will see if extra calcium…
Gastro
01 Jan 2013
Study of Inborn Errors of Cholesterol Synthesis and Related Disorders
This study will investigate the cause and medical problems associated with a group of genetic disorders known as inborn errors of cholesterol synthesis, in which the body does not produce cholesterol. People with this disorder may have birth defects and learning and behavioral problems. Official Title Investigations into Inborn Errors…
