Blood
01 Jan 2013
Sibling Donor Cord Blood Banking and Transplantation
To develop a national cord blood bank for siblings of patients with hemoglobinopathies, thalassemia and potentially malignant diseases. Official Title Sibling Donor Cord Blood Banking and Transplantation Conditions – Blood Disease- Anemia, Sickle Cell- Anemia (Cooley’s)- Leukemia- Bone Marrow Transplantation- Hematopoietic Stem Cell Transplantation Study Type Interventional Study Design…
Blood
01 Jan 2013
A Test to Predict the Hemolytic Potential of Drugs in G6PD Deficiency
This study will evaluate a new and safe testing method for identifying medicines that can cause problems in glucose-6-phosphate dehydrogenase (G6PD) deficient individuals. We are looking for volunteers with G6PD deficiency who would be willing to donate blood samples. Official Title A Test to Predict the Hemolytic Potential of Drugs…
Blood
01 Jan 2013
Severe Hemophilia A Study
To characterize the safety and efficacy of ReFacto AF in treating acute bleeding episodes during prophylaxis treatment, including neoantigenicity. Official Title An Open-label Study to Characterize the Safety and Efficacy of BDDrFVIII Manufactured by the Albumin Free Process (ReFacto AF) in the Treatment of Previously Treated Patients (PTP) with Severe…
Blood
01 Jan 2013
Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected with HIV
The purpose of this study is to find out whether these powerful combinations of anti-HIV drugs are safe and effective for use in patients in the early stages of HIV infection and to find out how patients’ immune systems react to HIV and anti-HIV drugs. Doctors generally treat patients in…
Cancer
01 Jan 2013
Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract
Vaccines may make the body build an immune response to kill tumor cells. Vaccines may make the body build an immune response to kill tumor cells.Randomizedphase II trial to compare the effectiveness of two different vaccines in treating patients who have cancer of the gastrointestinal tract. Condition:- Gastrointestinal CancerStudy Type:…
Cancer
01 Jan 2013
Bexarotene in Preventing Breast Cancer in Women at Genetic Risk
RATIONALE: Chemoprevention therapy uses certain drugs to try to prevent the development or recurrence of cancer. It is not yet known whether bexarotene is effective in preventing breast cancer. Official Title Randomized Chemoprevention Study of Bexarotene in Women at High Genetic Risk for Breast Cancer Conditions – Breast Cancer Study…
Cancer
01 Jan 2013
Screening Tests in Detecting Colorectal Cancer
RATIONALE: Screening tests may help doctors detect cancer cells early and plan more effective treatment for colorectal cancer. Official Title Randomized Screening Study of Fecal Occult Blood Testing and Multitarget DNA-Based Assay Panel Testing Followed By Colonoscopy in the Detection of Colorectal Cancer Conditions – Colon Cancer- Rectal Cancer Study…
Cancer
01 Jan 2013
Celecoxib in Preventing Breast Cancer in At-Risk Premenopausal Women
RATIONALE: Chemoprevention therapy uses certain drugs to try to prevent the development or recurrence of cancer. Celecoxib may be effective in preventing breast cancer in at-risk women. Official Title Phase II Chemoprevention Study of Celecoxib in Premenopausal Women at High Risk For Estrogen Receptor-Negative Breast Cancer Conditions -Breast Cancer Study…
Infections
01 Jan 2013
A Comparison of Two Ways to Manage Anti-HIV Treatment (The SMART Study)
The purpose of this study is to compare two ways of using anti-HIV drugs to help health care providers and patients decide how to best use anti-HIV treatments over many years. Many health care providers now treat patients with daily drugs to keep the viral load as low as possible.
