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The DIAMOND Study: Distensibility Improvement and Remodeling in Diastolic Heart Failure

The purpose of this study is to test the hypothesis that treatment with oral ALT-711 twice daily for 16 weeks…

01 Jan 2013

Identification of Genetic Markers for Cardiopulmonary Diseases (Genotype)

This study is designed to investigate whether an association exists between certain genes/protein levels and the development of various cardiopulmonary…

01 Jan 2013

Effect of Coffee on Gastro-Oesophageal Disease in Patients With Symptoms of Reflux

Investigation evaluating the effect of coffee on gastro-oesophageal reflux disease. Official Title Effect of Coffee on Gastro-Esophageal Disease in…

01 Jan 2013

BUILD 3: Bosentan Use in Interstitial Lung Disease

BUILD 3: Bosentan Use in Interstitial Lung Disease

BUILD 3 is a prospective, multicenter, randomized, double-blind, parallel group, placebo-controlled, event-driven, group sequential, phase III superiority study. The primary…

01 Jan 2013

Study Evaluating the Safety, Tolerability, and Efficacy of Lecozotan SR in Outpatients With Alzheimer’s Disease

The purpose of the study is to determine the safety, tolerability, and efficacy of 3 doses of lecozotan in combination…

01 Jan 2013

Blood Pressure and Glucose Lowering for the Prevention of Vascular Disease in High Risk Patients With Type 2 Diabetes.

The purpose of this study is to provide information on the risks and benefits of routine blood pressure lowering (regardless…

01 Jan 2013

A Trial of INO-1001 in Patients Undergoing Heart Surgery That Involves Heart-Lung Bypass

A Trial of INO-1001 in Patients Undergoing Heart Surgery That Involves Heart-Lung Bypass

The purpose of this study is to assess the safety of INO-1001, an intravenous PARP (poly-polymerase) inhibitor, in patients undergoing…

01 Jan 2013

Alternative Risk Markers in Coronary Artery Disease (ARMCAD)

The aim of this study is to assess several known and a few novel risk-factors (heart rate variability, pulse wave…

01 Jan 2013