Investigation evaluating the effect of coffee on gastro-oesophageal reflux disease.

Official Title

Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux.

Conditions

  • GERD

Study Type

Interventional

Study Design

Supportive Care, Open Label, Single Group Assignment, Efficacy Study.

Further Details

Primary Outcome Measures:

  • Coffee leads to reflux events
    [Time Frame: 48 hours]
    [Designated as safety issue: No]

Many patients with gastro-esophageal reflux disease (GERD) report that drinking coffee causes heartburn. The purpose of this study is to investigate the effects of coffee on gastro-esophageal acid reflux, and its relation to esophageal motility parameters in patients who are already scheduled to undergo 48 hour wireless pH testing as a result of having symptoms suggestive of GERD. The specific aims are to evaluate the effects of coffee on GERD during daily life and to elucidate the underlying pathogenic mechanism by which coffee induces reflux.

Study Start

May 2006

Eligibility & Criteria

  • Ages Eligible for Study: 18 Years and older
  • Genders Eligible for Study: Both
  • Accepts Healthy Volunteers: No

Inclusion Criteria:

  • Persons undergoing wireless pH testing for diagnosis and treatment of GERD

Exclusion Criteria:

  • Those under the age of 18
  • Pregnant and lactating women
  • Those who do not meet the inclusion criteria.

Total Enrolment

50

Contact Details

Peter Belafsky, (MD, PhD)
916-734-8181

Debbie Mouadeb, (MD)
916-734-8181

Location:

University of California Davis Medical Center
Sacramento, California
United States, 95817 

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