Children's health
01 Jan 2013
An Outpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder in Children and Adolescents
The purpose of this study is to determine the safety and effectiveness of Depakote ER (Divalproex Sodium Extended-Release Tablets) compared to placebo in the treatment of bipolar disorder, manic or mixed type in children and adolescents ages 10-17 years. Official Title Conditions Bipolar Disorder Study Type Interventional Study Design Treatment…
Bone
01 Jan 2013
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy, and Pharmacokinetics of the Human Anti-TNF Monoclonal Antibody Adalimumab in Children With Polyarticular Juvenile Rheumatoid Arthritis
This is a multicenter, Phase III randomized, placebo-controlled study in which polyarticular JRA subjects who are either MTX treated or non-MTX treated will initially receive Adalimumab by subcutaneous injection every other week for a four-month open-label lead-in period. Subjects who respond to the open-label therapy will then be rolled over…
Children's health
01 Jan 2013
Early Antipseudomonal Therapy in Cystic Fibrosis
To determine a safe, effective, and systematic approach to antibiotic treatment of Pseudomonas infection in young children with cystic fibrosis. Official Title Conditions – Cystic Fibrosis- Infection- Lung Diseases Study Type Interventional Study Design Prevention, Randomized Further Details BACKGROUND: Cystic fibrosis (CF), an autosomal recessive disorder without a cure,…
Children's health
01 Jan 2013
Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Children and Adolescent Patients with Bipolar I Mania
The purpose of this study is to demonstrate efficacy and safety of quetiapine fumarate (SEROQUEL) compared with placebo in the treatment of children and adolescent patients with Bipolar I mania. Official Title Conditions Bipolar Disorder Study Type Interventional Study Design Treatment, Placebo Control, Safety/Efficacy Study Further Details Study Start…
Children's health
01 Jan 2013
Safety and Efficacy Study of Etanercept (Enbrel) In Children with Systemic Onset Juvenile Rheumatoid Arthritis
This study will determine the efficacy of etanercept in children with systemically active systemic onset juvenile rheumatoid arthritis (SOJRA). Official Title Phase 3 Safety and Efficacy Study of Etanercept (Enbrel®) In Children with Systemic Onset Juvenile Rheumatoid Arthritis Conditions Arthritis, Juvenile Rheumatoid Study Type Interventional Study Design Treatment,…
Children's health
28 Dec 2012
Teen terminal illness blurs boundaries
Blurring professional and personal boundaries can sometimes happen when it comes to caring for adolescents and young adults (AYA) with a terminal illness, according to a Flinders University palliative care expert. Ms Kim Devery, a lecturer in the Department of Palliative and Supportive Services, and colleague Mrs Sharon…
Blood
21 Dec 2012
Intensified chemotherapy shows promise for children with very high-risk form of leukaemia
Young patients with an aggressive form of leukaemia who are likely to relapse after chemotherapy treatment can significantly reduce those odds by receiving additional courses of chemotherapy, suggest the findings of a clinical trial led by investigators at Dana-Farber/Children’s Hospital Cancer Center in Boston. The trial leaders will present the…
Children's health
17 Dec 2012
Preschool movement skills programs could lead to life-long benefits
Preschools could hold the key to kids developing a life-long interest in physical activity. Researchers with Deakin University’s School of Health and Social Development, with colleagues from Northern NSW Local Health District, evaluated a movement skills program run by NSW Health in 18 NSW preschools. The study, published in the…
Blood
14 Dec 2012
New research shows an interesting twist in the fight against malaria
New research published in the prestigious Science journal has challenged previous notions about how the body fights against malaria infection. Scientists have discovered that platelets, normally known for their role in preventing bleeding, can actually target and kill the parasite that causes malaria as it grows inside red blood cells.
