Gastro
01 Jan 2013
Study of Infliximab for the treatment of patients with active Ulcerative Colitis.
A research study to evaluate the safety and effectiveness of an investigational drug is currently being conducted in adults with moderate to severe ulcerative colitis. The aim of the international study is to evaluate the efficacy and safety of Infliximab in patients with active ulcerative colitis. The study is being…
Gastro
01 Jan 2013
Research Study in Patients With Severe Ulcerative Colitis
The purpose of the study is to evaluate an intravenous (by injection) investigational medication to treat severe ulcerative colitis refractory to steroid therapy. The research is being conducted at up to 8 clinical research sites in the US and is open to both men and women ages 18 to 70…
Gastro
01 Jan 2013
Immune Regulation in Ulcerative Colitis or Crohn’s Disease
This study will investigate in patients with Crohn’s disease and ulcerative colitis how the body’s immune system controls inflammation in the gastrointestinal tract (stomach and intestines)-specifically, how lymphocytes (a type of white blood cell) function in inflammatory responses. This protocol does not involve any experimental treatments. Official Title Studies of…
Gastro
01 Jan 2013
Treatment of Binge Eating Disorder
This is a multicenter (2 sites) randomized trial evaluating three group treatment models for subjects with binge eating disorder. One model is a cognitive behavior treatment (CBT) group, one is partial self help, and one is self help only. Official Title Conditions – Bulimia- Obesity Study Type Interventional Study…
Gastro
01 Jan 2013
Low-Dose Leptin and the Formerly-Obese
Our previous studies have demonstrated that there is substantial metabolic opposition to the maintenance of an altered body weight. Leptin is a protein secreted by fat cells and the circulating concentrations of leptin are directly proportional to fat mass. Leptin-deficiency is associated with severe obesity in rodents and in humans…
Gastro
01 Jan 2013
Strength Training Following Gastric Bypass for Obesity
We will assess whether undesirable loss of lean tissue following gastric bypass surgery for obesity can be minimized by protein supplementation and exercise training. Official Title Conditions – Obesity Study Type Interventional Study Design Treatment, Randomized, Open Label, Active Control, Factorial Assignment, Efficacy Study Further Details Study Start…
Cancer
01 Jan 2013
Open label study of ONTAK (denileukin diftitox) in previously treated Cutaneous T-cell Lymphoma patients.
The purpose of this study is to provide an opportunity for patients who exhibit progressive disease while receiving placebo on the companion 93-04-11 study to receive ONTAK. It is also designed to determine the effectiveness of ONTAK in CTCL patients whose tumors do not express CD25. Official Title A multicenter…
Heart
01 Jan 2013
Outcomes following myocardial revascularization: on and off cardiopulmonary bypass
Ischemic heart disease is one of the most frequent diagnoses in the VA system. Moreover, 5,819 coronary artery bypass graft (CABG-only) procedures were performed in the VA in FY 1999. Throughout VA and non-VA cardiac surgery programs nationwide, myocardial revascularization is now being performed using two surgical techniques. One technique…
Heart
01 Jan 2013
Efficacy and Cost Effectiveness of Relaxation and Response to CHF
Chronic heart failure (CHF) is a prevalent and costly disease. Because the incidence is higher among the elderly, the number of CHF patients is expected to rise as the population ages. Despite the development of significant pharmaceutical treatments, morbidity and mortality of CHF patients remain high, patients? quality of life…
