Bone
01 Jan 2013
Combination Chemotherapy and Peripheral Stem Cell Transplantation With or Without Radiation Therapy and/or Surgery in Treating Patients With Ewing’s Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. It is…
Cancer
01 Jan 2013
Bevacizumab to Treat Inflammatory Breast Cancer
This study will evaluate the effectiveness of the drug bevacizumab, in combination with doxorubicin and docetaxel, in improving survival of patients with inflammatory breast cancer. This aggressive breast cancer, which often causes a red, swollen, tender breast, is associated with a poor prognosis. Bevacizumab blocks the growth of new blood…
Bone
01 Jan 2013
Meditation-Based Stress Reduction in Rheumatoid Arthritis
The purpose of this study is to determine whether a mindfulness meditation-based stress reduction program is useful in relieving symptoms associated with rheumatoid arthritis (RA). Official Title Mindfulness Meditation-Based Stress Reduction in Relieving Symptoms Associated with Rheumatoid Arthritis Conditions – Rheumatoid Arthritis Study Type Interventional Study Design Educational/Counseling/Training, Randomized, Open…
Cancer
01 Jan 2013
GW572016 For Treatment Of Refractory Metastatic Breast Cancer
The purpose of this study is to determine the efficacy of an oral dual kinase inhibitor for the treatment of metastatic breast cancer tumors that are known to overexpress ErbB2 in a refractory patient population. Official Title Conditions – Metastatic breast cancer Study Type Interventional Study Design Treatment, Non-Randomized, Open…
Cancer
01 Jan 2013
A Dose-Escalation Vaccine Trial In HER2-Overexpressing Patients With High-Risk Breast Cancer
This trial will test how safe this vaccine is. It also tests whether its introduction induces an immune response by stimulating the patient’s own immune system to recognize a specific target molecule called HER2, which is overexpressed in many breast cancers. This trial will test how safe this vaccine is.
Heart
01 Jan 2013
A safety and efficacy trial evaluating the use of SanOrg34006 compared to warfarin or acenocoumarol in patients with atrial fibrillation
This trial will include patients who have a heart condition called atrial fibrillation. Atrial fibrillation is an abnormal rhythm (irregular beat) in the heart. Patients with atrial fibrillation have an increased chance for a blood clot to form in the heart and move to other blood vessels in the body…
Cancer
01 Jan 2013
Bexarotene in Preventing Breast Cancer in Women at Genetic Risk
RATIONALE: Chemoprevention therapy uses certain drugs to try to prevent the development or recurrence of cancer. It is not yet known whether bexarotene is effective in preventing breast cancer. Official Title Randomized Chemoprevention Study of Bexarotene in Women at High Genetic Risk for Breast Cancer Conditions – Breast Cancer Study…
Cancer
01 Jan 2013
Screening Tests in Detecting Colorectal Cancer
RATIONALE: Screening tests may help doctors detect cancer cells early and plan more effective treatment for colorectal cancer. Official Title Randomized Screening Study of Fecal Occult Blood Testing and Multitarget DNA-Based Assay Panel Testing Followed By Colonoscopy in the Detection of Colorectal Cancer Conditions – Colon Cancer- Rectal Cancer Study…
Cancer
01 Jan 2013
Celecoxib in Preventing Breast Cancer in At-Risk Premenopausal Women
RATIONALE: Chemoprevention therapy uses certain drugs to try to prevent the development or recurrence of cancer. Celecoxib may be effective in preventing breast cancer in at-risk women. Official Title Phase II Chemoprevention Study of Celecoxib in Premenopausal Women at High Risk For Estrogen Receptor-Negative Breast Cancer Conditions -Breast Cancer Study…
