Research and Trials

Cancer 01 Jan 2013

Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract

Vaccines may make the body build an immune response to kill tumor cells. Vaccines may make the body build an immune response to kill tumor cells.Randomizedphase II trial to compare the effectiveness of two different vaccines in treating patients who have cancer of the gastrointestinal tract. Condition:- Gastrointestinal CancerStudy Type:…
Fondaparinux Use in a Broad Range of Patients with ST-segment Elevation Acute Myocardial Infarction (MI)
Heart 01 Jan 2013

Fondaparinux Use in a Broad Range of Patients with ST-segment Elevation Acute Myocardial Infarction (MI)

The purpose of this research study is to determine the efficacy and safety of fondaparinux (Arixtra) in preventing death and repeat heart attacks and their complications. Official Title Safety and efficacy trial evaluating fondaparinux use in a broad range of patients with ST segment elevation acute MI Conditions – Myocardial…
APPLES: Apnea Positive Pressure Long-Term Efficacy Study
Lungs 01 Jan 2013

APPLES: Apnea Positive Pressure Long-Term Efficacy Study

To determine the effectiveness of nasal continuous positive airway pressure (CPAP) therapy for the treatment of obstructive sleep apnea syndrome. Official Title – Lung Diseases- Sleep Apnea Syndromes- Sleep Conditions Study Type Interventional Study Design Treatment, Randomized Further Details BACKGROUND: Nasal continuous positive airway pressure (CPAP) therapy is in widespread…
Bone 01 Jan 2013

Absorption and Distribution of Glucosamine and Chondroitin

The purpose of this study is to examine the way the dietary supplements glucosamine and chondroitin are absorbed and distributed throughout the body. Official Title A Pharmacokinetic Study of Glucosamine and Chondroitin Conditions Osteoarthritis Study Type Interventional Study Design Treatment, Randomized, Open Label, Uncontrolled, Parallel Assignment, Pharmacokinetics Study Further Details…
Lungs 01 Jan 2013

OPUS Study: Effect of Roflumilast on exacerbation rate in patients with chronic obstructive pulmonary disease

The purpose of this study is to determine whether roflumilast is effective in the treatment of exacerbations in patients with chronic obstructive pulmonary disease (COPD). Official Title Conditions – Chronic Obstructive Pulmonary Disease Study Type Interventional Study Design Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study Further Details Study…
Lungs 01 Jan 2013

Safety Study of the Aeris Bronchoscopic Lung Volume Reduction (BLVR) System in Patients with Advanced Emphysema

The purpose of this study is to determine whether the Aeris Bronchoscopic Lung Volume Reduction (BLVR) System is safe in patients with advanced emphysema. Official Title A Single-center, Non-blinded, Non-randomized, Non-controlled Phase 1 Trial Assessing the Safety of the Aeris Therapeutics Bronchoscopic Lung Volume Reduction (BLVR) System in Patients with…
Lungs 01 Jan 2013

Segmental Bronchoalveolar Lavage

Bronchoalveolar lavage is a diagnostic and therapeutic procedure conducted by placing a fiberoptic scope into the lung of a patient, and injecting sterile water (saline) into the lung and removing. The sterile water removed contains secretions, cells, and protein from the lower respiratory tract. This sample can be analyzed to…
Lungs 01 Jan 2013

Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD)

The purpose of this study is to determine whether genetic factors contribute to an individuals risk of developing obstructive lung disease from smoking cigarettes. Official Title Genetic Mechanisms of Chronic Obstructive Pulmonary Disease Conditions – Chronic Obstructive Lung Disease Study Type Observational Study Design Screening, Cross-Sectional, Defined Population, Retrospective Study…
Bone 01 Jan 2013

Pegvisomant and Sandostatin LAR Combination Study

To compare the safety and tolerability of combination therapy with Sandostatin LAR plus Pegvisomant to that of Sandostatin LAR alone or Pegvisomant alone. To compare the safety and tolerability of combination therapy with Sandostatin LAR plus Pegvisomant to that of Sandostatin LAR alone or Pegvisomant alone.Condition:- AcromegalyStudy Type: InterventionalStudy Design:…