Blood
27 Apr 2013
Lymphatic System
The lymphatic system the body's secondary circulatory system. Its functions are closely linked to the functions of the body's primary circulatory system, the blood circulation. Organs and cells of the lymphatic system play an integral role in supporting the immune system, which is a functional system consisting of cells (e.g. blood cells which fight infection) and molecules (e.g. antibodies which protect against particular diseases). Unlike other body systems the immune system has no organs.
Children's health
29 Jan 2013
Adolescent stress linked to severe adult mental illness
Working with mice, Johns Hopkins researchers have established a link between elevated levels of a stress hormone in adolescence – a critical time for brain development – and genetic changes that, in young adulthood, cause severe mental illness in those predisposed to it. The findings, reported in the journal Science,…
Heart
01 Jan 2013
CAROLINA: Cardiovascular Outcome Study of Linagliptin versus Glimepiride in Patients with Type 2 Diabetes
The aim of the study is to investigate the long-term impact on cardiovascular morbidity and mortality, relevant efficacy parameters (e.g., glycaemic parameters) and safety (e.g., weight and hypoglycaemia) of treatment with linagliptin in patients with type-2 diabetes at elevated cardiovascular risk receiving usual care, and compare outcome against glimepiride. Official…
Children's health
01 Jan 2013
Metabolic Phenotyping of Individuals Born Following Assisted Reproduction Techniques (IMPART)
This study is to compare the effects of high-fat overfeeding on metabolic risk factors in children born through assisted reproduction technologies (ART) versus children conceived naturally (controls). We will utilise state of the art measures to characterise the physiological, endocrine and molecular responses to high fat overfeeding. The investigators…
Hormones
01 Jan 2013
Vitamin D in Vietnamese Research Project
A current research project aims to build on the results of an earlier study which revealed that Vitamin D deficiency is as high as 88% (9 out of 10 people) in Vietnamese living in Melbourne. Research will now assess the effectiveness of Vitamin D supplements in the treatment of Graves’…
Cancer
01 Jan 2013
Phase 3 Study of Immunotherapy to Treat Advanced Prostate Cancer
The purpose of this study is to determine if patients with metastatic prostate cancer who have not received chemotherapy live longer when treated with ipilimumab than those treated with a placebo. Official Title Randomized, Double-Blind, Phase 3 Trial to Compare the Efficacy of Ipilimumab vs Placebo in Asymptomatic or Minimally…
Hormones
01 Jan 2013
Effect of Growth Hormone on Insulin Signaling in Muscle Tissue
The purpose of this study is to examine the effects of a physiological bolus of growth hormone on insulin signaling pathways in muscle tissue in healthy lean men. Official Title The Effect of a Physiological Bolus of Growth Hormone (GH) on Insulin Signaling Pathways in Muscle Tissue From Healthy Adults…
Hormones
01 Jan 2013
Thyroxine Titration Study
The aim of the study is to examine the effects of fine titration of thyroxine dosage on symptoms of hypothyroidism, wellbeing and quality of life. The hypothesis is that symptoms of hypothyroidism, wellbeing and quality of life will be improved in thyroxine-treated subjects when serum thyrotropin (TSH) is suppressed and/or…
Hormones
01 Jan 2013
Trial of Growth Hormone Therapy in Paediatric Crohn’s Disease
The purpose of this study is to determine whether taking a growth hormone (GH) drug called somatropin causes the intestine of a person with Crohn’s disease (CD) to heal faster when compared to a person with Crohn’s disease that does not receive growth hormone drug. Official Title A Phase II…
