Gastro
01 Jan 2013
A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associated Diarrhea
This study aims to determine if an investigational drug is safe and effective for treating symptoms of C. difficile-associated diarrhea (CDAD) and lowering the risk of repeat episodes of CDAD. The investigational drug will be evaluated in comparison to current standard antibiotic treatment, so all patients will receive active medication.
Gastro
01 Jan 2013
A Study of Visilizumab in Subjects With Intravenous Steroid-Refractory Ulcerative Colitis
The purpose of this study is to compare the efficacy of visilizumab to placebo in subjects with intravenous steroid-refractory ulcerative colitis. Official Title A Phase 2/3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Visilizumab in Subjects With Intravenous Steroid-Refractory Ulcerative Colitis Conditions Ulcerative Colitis Study Type Interventional Study Design Treatment,…
Cancer
01 Jan 2013
A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum
fThis is a multi-centre randomised trial comparing long course (LC) preoperative chemoradiation with short course (SC) preoperative radiotherapy for patients with localised T3 rectal cancer. Official Title A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum Conditions Adenocarcinoma of Rectum Study Type Interventional Study Design…
Gastro
01 Jan 2013
ASTERIX: Low Dose ASA and Nexium
The purpose of the study is to evaluate the effect of esomeprazole 20 mg od versus placebo for the prevention of gastric and/or duodenal ulcers in patients taking low-dose ASA. Official Title A Randomized Double-Blind Placebo-Controlled Study to Assess the Prevention of Low-Dose Acetylsalicylic Acid (ASA) Associated Gastroduodenal Lesions and…
Gastro
01 Jan 2013
Cirrhotic Ascites Treatment With Satavaptan in Patients With Ascites Due to Cirrhosis of the Liver (CATS)
To evaluate the efficacy of satavaptan on top of conventional treatment in the treatment of clinically evident ascites in patients with cirrhosis of the liver and to evaluate the tolerability and safety of satavaptan over a 52-week treatment period in patients with cirrhosis of the liver and ascites. Official Title…
Children's health
01 Jan 2013
An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children
The purpose of this study was to evaluate the safety and efficacy of Movicol in the treatment of chronic constipation in children. Official Title An Open Single Centre Study To Assess the Safety and Efficacy of Movicol in the Treatment of Chronic Constipation in Children Conditions Chronic Constipation Study Type…
Gastro
01 Jan 2013
A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)
This study will test the hypothesis that GW427353, a beta-3 adrenergic agonist, will relieve IBS pain or discomfort and associated symptoms in IBS patients. Official Title A Randomized, Double-Blind, Placebo-Controlled, Crossover, Phase IIa Study to Evaluate Efficacy and Safety of the Beta-3-Adrenergic Receptor Agonist Solabegron in Subjects With Irritable Bowel…
Gastro
01 Jan 2013
A Study of Abatacept in Patients With Active Crohn’s Disease
The purpose of this clinical research study is to learn if abatacept can improve signs and symptoms of active Crohn’s Disease in patients who have not had an adequate response to other therapies. The safety of this treatment will also be studied. Official Title A Phase 3, Multi-Center, Randomized, Placebo-Controlled…
Gastro
01 Jan 2013
Study of Dexlansoprazole vs Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis.
A 6-month study to assess the ability of daily treatment with dexlansoprazole 30mg, 60 mg or placebo in maintaining healing of erosive esophagitis. Official Title A Phase 3 Study to Evaluate the Safety and Efficacy of TAK-390MR (30 mg QD and 60 mg QD) Compared to Placebo in Maintenance of…
