Gastro
01 Jan 2013
Study of Esomeprazole 20 mg or 40 mg vs Placebo Effectiveness on the Occurrence of Peptic Ulcers in Subjects on LDA (Oberon)
The purpose of this study is to compare the effect of esomeprazole 20 and 40 mg once daily versus placebo on the occurrence of peptic ulcers during 26 weeks in subjects on continuous low-dose acetylsalicylic acid. Official Title A Randomized, Double-Blind, Parallel-Group, Multicentre, Phase III Study to Assess the Effect…
Cancer
01 Jan 2013
PRIME: Panitumumab Randomized Trial In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy
The purpose of this study is to determine the treatment effect of panitumumab in combination with FOLFOX compared to FOLFOX alone as first line therapy for metatstatic colorectal cancer Official Title A Randomized, Multicenter, Phase 3 Study to Compare the Efficacy of Panitumumab in Combination With Oxaliplatin/ 5-Fluorouracil/ Leucovorin to…
Gastro
01 Jan 2013
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-Abdominal Infection (cIAI)
This is a study of the safety and efficacy of tigecycline to ceftriaxone sodium plus metronidazole in hospitalized subjects with cIAI. Subjects will be followed for efficacy through the test-of-cure assessment. Safety evaluations will occur through the treatment and post-treatment periods and continue through resolution or stability of the adverse…
Gastro
01 Jan 2013
A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis
Erosive Esophagitis Clinical Trial
Gastro
01 Jan 2013
Study of Visilizumab Versus Placebo in Subjects With Intravenous Steroid-Refractory Ulcerative Colitis Previously Responsive in a Visilizumab Study
Ulcerative Colitis Clinical Trial
Cancer
01 Jan 2013
Two Chemotherapy Regimens Compared With Observation in Treating Patients With Completely Resected Pancreatic Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which chemotherapy regimen is more effective, or whether chemotherapy is more effective than observation, in treating pancreatic cancer after surgery. PURPOSE: Phase III trial…
Cancer
01 Jan 2013
Eflornithine and Sulindac in Preventing Colorectal Cancer in Patients With Colon Polyps
Rationale: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eflornithine and sulindac may prevent colorectal cancer. It is not yet known whether eflornithine and sulindac are more effective than a placebo in preventing colorectal cancer. Purpose: This randomized…
Gastro
01 Jan 2013
Probiotic and Crohn’s Disease Study
Probiotics are a food supplement containing living microorganisms, which upon ingestion in certain numbers exert health benefits beyond inherent basic nutrition. They have been shown to reduce intestinal inflammation in the inflammatory bowel diseases, Crohn’s disease (CD) and ulcerative colitis (UC). Probiotics are effective in the treatment of acute pouchitis…
Cancer
01 Jan 2013
A Feasibility Study to Evaluate Adjuvant Chemoradiotherapy for Gastric Cancer
The purpose of this study is to determine the side-effects and effectiveness of a new type of chemoradiotherapy treatment for patients who have had surgery for stomach cancer. The treatment uses epirubicin, cisplatin, and 5-fluorouracil (ECF) chemotherapy together with radiotherapy. Official Title Conditions Gastric Cancer Study Type Interventional Study Design…
