Bone

Bone 01 Jan 2013

Abatacept and Infliximab in Combination with Methotrexate in Subjects with Rheumatoid Arthritis

The purpose of this clinical research study is to learn if Abatacept in combination with Methotrexate and Infliximab demonstrate a greater reduction in disease activity over placebo. Official Title A Phase III, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Comparative Study of Abatacept or Infliximab in Combination with Methotrexate in Controlling Disease Activity…
Bone 01 Jan 2013

Effects of Arzoxifene on Bone Fractures and Incidence of Breast Cancer

The purpose of this trial is to study: – Effects of arzoxifene on bone fractures and bone mass. – Effects of arzoxifene on getting breast cancer. – Effects of arzoxifene on certain types of cardiovascular events, such as heart attack and stroke. – Effects of arzoxifene that…
Bone 01 Jan 2013

International Registry for Severe Chronic Neutropenia

Document the clinical course of severe chronic neutropenia (SCN). II. Monitor and assess long term safety of primary treatment in SCN patients in the United States, Canada, Europe, and Australia. III. Study the incidence and outcome of adverse events such as osteoporosis, splenomegaly, cytogenetic abnormalities, myelodysplastic syndrome, and leukemia. IV.
Bone 01 Jan 2013

A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly

The pupose of the study is to determine if Pegvisomant is more efficacious than Sandostatin LAR Depot in normalizing IGF-I levels in treatment naive patients with acromegaly. Condition:- Acromegaly Study Type: InterventionalStudy Design: Treatment Eligibility Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both Criteria Other…
Bone 01 Jan 2013

Absorption and Distribution of Glucosamine and Chondroitin

The purpose of this study is to examine the way the dietary supplements glucosamine and chondroitin are absorbed and distributed throughout the body. Official Title A Pharmacokinetic Study of Glucosamine and Chondroitin Conditions Osteoarthritis Study Type Interventional Study Design Treatment, Randomized, Open Label, Uncontrolled, Parallel Assignment, Pharmacokinetics Study Further Details…
Bone 01 Jan 2013

Pegvisomant and Sandostatin LAR Combination Study

To compare the safety and tolerability of combination therapy with Sandostatin LAR plus Pegvisomant to that of Sandostatin LAR alone or Pegvisomant alone. To compare the safety and tolerability of combination therapy with Sandostatin LAR plus Pegvisomant to that of Sandostatin LAR alone or Pegvisomant alone.Condition:- AcromegalyStudy Type: InterventionalStudy Design:…
Bone 01 Jan 2013

Combination Chemotherapy and Peripheral Stem Cell Transplantation With or Without Radiation Therapy and/or Surgery in Treating Patients With Ewing’s Sarcoma

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy and kill more tumor cells. It is…
Bone 01 Jan 2013

Meditation-Based Stress Reduction in Rheumatoid Arthritis

The purpose of this study is to determine whether a mindfulness meditation-based stress reduction program is useful in relieving symptoms associated with rheumatoid arthritis (RA). Official Title Mindfulness Meditation-Based Stress Reduction in Relieving Symptoms Associated with Rheumatoid Arthritis Conditions – Rheumatoid Arthritis Study Type Interventional Study Design Educational/Counseling/Training, Randomized, Open…
Bone 01 Jan 2013

Joint Injections for Osteoarthritic Knee Pain

The purpose of this study is to determine whether prolotherapy, a therapy based on injection of a sugar solution in and around the knee, can decrease pain and disability from knee osteoarthritis (OA). Official Title The Efficacy of Prolotherapy in Osteoarthritic Knee Pain Conditions -Treatment or Intervention Phase -Osteoarthritis-Procedure: Prolotherapy-Phase…