Effects of Arzoxifene on Bone Fractures and Incidence of Breast Cancer

The purpose of this trial is to study:

– Effects of arzoxifene on bone fractures and bone mass.
– Effects of arzoxifene on getting breast cancer.
– Effects of arzoxifene on certain types of cardiovascular events, such as heart attack and stroke.
– Effects of arzoxifene that changes the amount of certain substances in the blood that are related to osteoporosis and cardiovascular health.
– Effects of arzoxifene on the uterus.
– The safety of arzoxifene and any side effects.

Official Title

Effects of Arzoxifene on Bone Fractures and Incidence of Breast Cancer

Conditions

Osteoporosis, Postmenopausal

Study Type

Interventional

Study Design

Treatment, Safety/Efficacy Study

Further Details

Study Start

July 19, 2004

Eligibility & Criteria

Inclusion Criteria:- 60-85 years of age – Female – At least two years since last menstrual cycle Exclusion Criteria:- Abnormal or unexplained vaginal bleeding. – Bone disorders, other than osteoporosis or low bone mass – History of breast cancer, cancer of the uterus, or any cancer in the last five years (except skin cancer). – History of cerebral vascular accidents or venous thromboembolic events – Medications outlined

Total Enrolment

Contact Details

Recruitment and information available at a number of Australian centers, please call, for additional information regarding investigative sites for this trial, 1-877-285-4559.