Bone
01 Jan 2013
Tai Chi or Hydrotherapy for People With Osteoarthritis of the Hip(s) or Knee(s)
The aim of this study is to determine, in the framework of a randomized controlled clinical trial, whether Tai Chi can affect measurable improvements in self-reported outcomes such as pain, physical function and psychological well-being in people with osteoarthritis (OA) mainly affecting the hips or knees. The effectiveness of Tai…
Bone
01 Jan 2013
A Clinical Study in the Use of Orthotics in Treating Pain in the Front of the Knee
This project will conduct a randomised clinical trial to evaluate the relative benefits of orthotics as the sole treatment of patellofemoral pain syndrome and also when combined with physiotherapy. Factors associated with predicting the results of orthotic therapy will be studied to see if there are any tests that a…
Bone
01 Jan 2013
Zoledronic Acid Treatment of Spontaneous Osteonecrosis of the Knee
This study will assess the safety and efficacy of zoledronic acid in patients presenting with spontaneous osteonecrosis of the knee. Official Title A Randomized, Double-Blind, Placebo-Controlled, Proof of Concept Study of Zoledronic Acid in Spontaneous Osteonecrosis of the Knee (SONK) Conditions Osteonecrosis Study Type Interventional Study Design Treatment, Randomized, Double-Blind,…
Bone
01 Jan 2013
A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease
This study will compare the efficacy of intravenous Bondronat with that of zoledronic acid in patients with malignant bone disease experiencing moderate to severe pain. The anticipated time of study treatment is 6-12 months, and the target sample size is 100-500 individuals Official Title A Randomized, Placebo-Controlled, Double-Blind Study of…
Bone
01 Jan 2013
Long Term Efficacy and Safety of Zoledronic Acid Treatment in Patients With Bone Metastases
This study is designed to monitor the safety and efficacy of long-term treatment with zoledronic acid by assessing the incidence of, renal impairment, osteonecrosis of the jaw(ONJ), overall safety and skeletal related events (SREs) beyond 12 months treatment Official Title A Phase IV Study of Zoledronic Acid Therapy in Patients…
Bone
01 Jan 2013
Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing’s Sarcoma
This randomized phase III trial is studying different combination chemotherapy regimens to see how well they work when given with or without peripheral stem cell transplantation, radiation therapy, and/or surgery in treating patients with Ewing’s sarcoma Official Title EURO-E.W.I.N.G. 99 – European Ewing Tumour Working Initiative of National Groups –…
Bone
01 Jan 2013
Study Evaluating the Safety and Efficacy of a Once-Daily Dose of Tigecycline vs Ertapenem in Diabetic Foot Infections with Osteomyelitus
This purpose of this study is to look at the safety and effectiveness of a once-daily dose of tigecycline compared to ertapenem for the treatment of diabetic foot infections with osteomyelitis. Official Title A Multicenter, Randomized, Double-Blind, Comparison Study of the Safety and Efficacy of a Once-Daily Dose of Tigecycline…
Bone
01 Jan 2013
Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia
This randomised controlled trial will evaluate the role of manual therapy and therapeutic exercise and corticosteroid injections in the treatment of lateral epicondylalgia (tennis elbow). Official Title A Pragmatic, Randomised Controlled Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia Conditions Tennis Elbow, Musculoskeletal Diseases Study Type Interventional Study Design…
Bone
01 Jan 2013
A Study to Compare MPR With MP in Newly Diagnosed Multiple Myeloma Subjects 65 Years Old or Older
Phase III randomised study to compare MPR with MP in newly diagnosed Multiple Myeloma subjects who are 65 years old or older. Official Title A Phase III, Multicentre, Randomised, Double-Blind, Placebo-Controlled, 3 Arm Parallel-Group Study to Determine the Efficacy and Safety of Lenalidomide (Revlimid) in Combination With Melphalan and Prednisone…
