Blood
01 Jan 2013
Treatment of Deficient Subclass or Anti-Polysaccharide Antibody
There is no consensus on the treatment of patients with recurrent infections and isolated immunoglobulin G (IgG)-subclass deficiency and/or selective antipolysaccharide antibody deficiency. Therefore, the Dutch Inter University Working Party will start a study in which the treatment with antibiotics is compared with intravenous immunoglobulin therapy with respect to clinical…
Blood
01 Jan 2013
Pesticides in the Households of Healthy Volunteers and Young Patients With Leukaemia
Rationale: Learning about pesticides in the households of young patients with leukaemia and in the households of healthy volunteers may help scientists better understand the risk of leukaemia.Purpose: This epidemiology study is identifying environmental factors related to the risk of leukaemia in the households of healthy volunteers and in the…
Blood
01 Jan 2013
Characteristics of Blood-Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood-brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and neuroanatomical alterations. Official Title Blood-Brain Barrier Permeability in Neurological Patients: Anatomical, Neurophysiological, and Clinical Characteristics. Conditions Traumatic…
Blood
01 Jan 2013
Iron Sucrose in Stage 3/4 Kidney Disease
Blood
01 Jan 2013
Sequestration of Platelets Prior to Bypass Reduces Bleeding After Cardiac Surgery
Excessive bleeding is common after cardiac surgery. This may result in patients receiving a blood transfusion or suffering the life-threatening complication of cardiac tamponade. Tamponade is when excessive bleeding compresses the heart and prevents it from pumping properly. A major reason for the bleeding is the damage done to platelets…
Blood
01 Jan 2013
Ezetimibe/Simvastatin in Patients With Metabolic Syndrome
A 6-week clinical trial in patients with metabolic syndrome and hypercholesterolemia at high risk for coronary heart disease to study the effects of ezetimibe/simvastatin and atorvastatin on lipids. Official Title A Multicenter, Randomized, Double-Blind, Parallel Arm, 6-Week Study to Evaluate the Efficacy and Safety of Ezetimibe/Simvastatin Versus Atorvastatin in Patients…
Blood
01 Jan 2013
High Density Lipoprotein Turnover
The objective of the study is to evaluate the effect of Rimonabant 20mg in comparison to placebo, on HDL and VLDL lipoprotein kinetics, over a 12 months period. Official Title A Randomized, Double-Blind, Two Arm, Parallel, Placebo Controlled Study of Rimonabant 20 mg Effect on High Density Lipoprotein Kinetics in…
Blood
01 Jan 2013
Study to Assess If Internet-Based Tailored Advice Could Modify Behaviour to Improve Health
The purpose of this trial is to find out if a special website might help people discover if they have high cholesterol and then enable them to manage their cholesterol more appropriately. The primary aim of this trial is to determine the effects on consumers’ use of cholesterol lowering therapy…
Blood
01 Jan 2013
Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol
This study will evaluate the lipid-lowering effect and safety of colesevelam therapy administered to heterozygous familial pediatric patients 10 through 17 years of age who are on a stable dose of a pediatric-approved statin monotherapy (atorvastatin, lovastatin, simvastatin or pravastatin), or who are treatment naive to lipid-lowering therapy. Official Title…
