Blood

Tobacco smoke harms teenage kidneys
Blood 26 Apr 2013

Tobacco smoke harms teenage kidneys

A fun party game, musicial statues is also a great way for kids to practice listening, socialising and develop motor skils and coordination.
Do non-steroidal anti-inflammatory drugs cause kidney failure in children?
Blood 12 Feb 2013

Do non-steroidal anti-inflammatory drugs cause kidney failure in children?

Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, are commonly used to treat pain and reduce fever in children. However, the use of NSAIDs has been shown to cause acute kidney injury (AKI) in some children. A new study scheduled for publication in The Journal of Pediatrics reports the…
Blood 01 Jan 2013

Nasal Application of 5% Tea Tree Oil (TTO) Versus Mupirocin for the Prevention of Catheter-associated Infections in Renal Dialysis Patients

This study will compare the use of tea tree oil against mupirocin as a topical nasal antiseptic to see which is best at preventing infections in patients that need renal dialysis. Fifty subjects will be recruited into each arm of the trial and will be assessed for signs of infection…
Blood 01 Jan 2013

A Study Evaluating Safety and Immunogenicity of Meningococcal B rLP2086 Vaccine in Adolescents

The purpose of this study is to evaluate the safety and immunogenicity of an investigational meningococcal B rLP2086 vaccine in adolescents aged 11 to 18…
Blood 01 Jan 2013

Treatment of Deficient Subclass or Anti-Polysaccharide Antibody Response (Subklasse)

There is no consensus on the treatment of patients with recurrent infections and isolated immunoglobulin G (IgG)-subclass deficiency and/or selective antipolysaccharide antibody deficiency. Therefore, the Dutch Inter University Working Party will start a study in which the treatment with antibiotics is compared with intravenous immunoglobulin therapy with respect to clinical…
Blood 01 Jan 2013

Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy

Autosomal-Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary renal disease, characterised by the progressive development of fluid-filled cysts in the kidney leading to progressive loss of renal function and eventually to renal failure. It is responsible for 8% to 10% of the cases of end stage renal disease…
Blood 01 Jan 2013

GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies

The purpose of this study is to investigate whether the addition of a vaccine after participants reduced intensity transplant will be safe and beneficial. The vaccine used in this trial, called GVAX, will be made from the participants own leukaemia cells, and will be given between 1-4 months after transplant.
Blood 01 Jan 2013

Study to Determine the Effect and Safety of an Oral Janus Kinase 2 (JAK2)-Inhibitor in Patients with Multiple Myeloma

The purpose of this study is to determine clinical efficacy and safety of INCB018424, a small molecule Janus kinase (JAK) inhibitor, in patients with refractory or relapsed multiple myeloma. Official Title A Phase 2, Two Stage, Open-Label, Clinical Trial to Determine the Therapeutic Effect and Safety of an Oral JAK2-Inhibitor…
Blood 01 Jan 2013

Intravenous Iron in Patients With Anaemia of Chronic Kidney Disease

The objective of this study is the evaluation of the efficacy and safety of intravenous iron sucrose in anaemic patients with chronic kidney disease not on renal replacement therapy. Official Title Open Randomized Phase IV Study on Intravenous Iron in Anemic Patients With Chronic Kidney Disease. Conditions Chronic…