Blood
01 Jan 2013
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy
Autosomal-Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary renal disease, characterised by the progressive development of fluid-filled cysts in the kidney leading to progressive loss of renal function and eventually to renal failure. It is responsible for 8% to 10% of the cases of end stage renal disease…
Cancer
01 Jan 2013
Effect of Dietary, Lifestyle, and Environmental Factors on Patients With Early-Stage Bladder Cancer
Rationale: Learning about the long-term effects of dietary, lifestyle, and environmental factors on the risk of cancer progression and recurrence may help the study of bladder cancer in the future.Purpose: This clinical trial is studying how dietary, lifestyle, and environmental factors affect patients with early-stage bladder cancer.
Official TitleBladder Cancer Prognosis Programme (Incorporating SELENIB Trial).
Blood
01 Jan 2013
Intravenous Iron in Patients With Anaemia of Chronic Kidney Disease
The objective of this study is the evaluation of the efficacy and safety of intravenous iron sucrose in anaemic patients with chronic kidney disease not on renal replacement therapy. Official Title Open Randomized Phase IV Study on Intravenous Iron in Anemic Patients With Chronic Kidney Disease. Conditions Chronic…
Blood
01 Jan 2013
Iron Sucrose in Stage 3/4 Kidney Disease
Research and Trials
01 Jan 2013
PRIDE – Prograf Investigation of Diet and Exercise. A Pilot Trial of the Effect of Dietary and Exercise Intervention in Patients Who Have Received a Renal Transplant on Tacrolimus (Prograf)
The purpose of this trial is to investigate whether a combined dietary and exercise intervention, added to standard care, reduces the expected frequency of insulin resistance in kidney transplant recipients on tacrolimus. Official Title A Pilot Trial of the Effect of Dietary and Exercise Intervention on Insulin Resistance and Metabolic…
Research and Trials
01 Jan 2013
Audit of the Effect of Changing From Intravenous to Subcutaneous Administration of Erythropoeisis Stimulating Agents in Haemodialysis Patients
The purpose of this study is to audit the effects of changing all haemodialysis patients from intravenous to subcutaneous administration of ESA’s, to ensure that a cost-saving is achieved and that this does not occur at the expense of anaemia control. The dose changes will occur according to usual clinical…
Blood
01 Jan 2013
A Study of NeoRecormon (Epoetin Beta) in Patients With Renal Anemia
This study will determine whether 8 weekly monitoring of hemoglobin and iron parameters in the correction phase of NeoRecormon therapy in patients with renal anemia is as safe and effective as 4 weekly monitoring. Patients with chronic kidney disease will receive NeoRecormon at a dose aimed at achieving and maintaining…
Men's Health
01 Jan 2013
Study The Effects Of Different Doses Of UK-369,003 In Men With Overactive Bladder.
This is a 12 week study in which different doses of UK-369,003 will be administered to patients with a diagnosis of overactive bladder. Patients will complete a series of questionnaires before treatment, during treatment and after treatment, to assess whether UK-369,003 has improved their symptoms of overactive bladder and erectile…
Cancer
01 Jan 2013
GW786034 In Subjects With Locally Recurrent Or Metastatic Clear Cell Renal Cell Carcinoma
Phase II, multi-center, two-stage study utilising a randomised discontinuation design to evaluate the safety and efficacy of GW786034 in adult subjects with locally recurrent or metastatic clear-cell Renal Cell Carcinoma (RCC). Official Title A Phase II Study of GW786034 Using a Randomised Discontinuation Design in Subjects With Locally Recurrent or…
