Research and Trials
01 Jan 2013
A Study to Assess Use of Zenapax (Daclizumab) and CellCept (Mycophenolate Mofetil) to Improve Kidney Function in Kidney Transplant Patients
This study will compare kidney function in kidney transplant patients following treatment with various combinations of Zenapax, CellCept, corticosteroids, and Neoral (Cyclosporine). The anticipated time on study treatment is 6-12 months, and the target sample size is 500+ individuals. Official Title A Randomized, Open-Label Study Comparing the Effects of Low-Dose…
Hormones
01 Jan 2013
E.V.O.L.V.E. Trial: EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events
This study will evaluate the effects of cinacalcet (cincalcet HCl or Sensipar/Mimpara) on cardiovascular events and death in chronic kidney disease (CKD) patients with secondary hyperparathryoidism (HPT) who are receiving dialysis. Official Title EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events Conditions Secondary Hyperparathyroidism, Chronic Kidney Disease Study Type…
Hormones
01 Jan 2013
The DURABLE Trial: Evaluating the Durability of Starter Insulin Regimens in Patients With Type 2 Diabetes
This study will compare insulin lispro low mixture and insulin glargine in combination with the patient’s oral diabetes medicines for their ability to control blood sugar in patients with type 2 diabetes and compare insulin lispro LM to insulin glargine with regard to the length of time that the overall…
Blood
01 Jan 2013
Super High-Flux – High Volume Dialysis in Sepsis-Induced Acute Renal Failure
We wish to compare the effect of using new large hole filters with hemodialysis in patients with severe infections and acute kidney failure to that of standard filters. The new therapy will be considered to be effective if it lowers the amount of drugs used to support blood pressure and…
Research and Trials
01 Jan 2013
Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis
The purpose of this clinical research study is to learn if abatacept treatment of patients with active lupus nephritis who are also taking mycophenolate mofetil (MMF) and steroids as part of this study will control the nephritis despite a protocol-defined steroid taper; the endpoint is a “complete renal response”, a…
Blood
01 Jan 2013
Trial to Reduce Cardiovascular Events With ‘Aranesp’ Therapy (TREAT)
The purpose of this study is to assess the impact of treatment of anemia with darbepoetin alfa on mortality and cardiovascular morbidity in patients with chronic kidney disease and type 2 diabetes. Official Title Conditions Kidney Disease, Nephritis, Diabetes Mellitus, anaemia Study Type Interventional Study Design Treatment Further Details Primary…
Research and Trials
01 Jan 2013
Study of Long-Term Living Kidney Donors
This study is designed to quantify the long-term medical and psychosocial implications of living kidney donation. The short-term consequences of living donation are well established. On the other hand the long-term consequences of living kidney donation are far less certain. The main medical concerns of living kidney donation include an…
Heart
01 Jan 2013
Telmisartan vs. Losartan for Improvement of Renal Function in Hypertensive Diabetic Patients With Overt Nephropathy.
A number of blood pressure lowering drugs in the class known as angiotensin receptor blockers (ARB) have been shown to slow the decline in kidney function of patients with type 2 diabetes, high blood pressure, and kidney disease. Losartan (COZAAR), is one such drug. The purpose of this research study…
Cancer
01 Jan 2013
SU011248 Versus Interferon-Alfa As First-Line Systemic Therapy For Patients With Metastatic Renal Cell Carcinoma
The purpose of this study is to test whether SU011248 has activity and is safe compared to interferon-alfa as first-line therapy in patients with metastatic renal cell carcinoma (RCC). Official Title A Phase 3, Randomized Study Of SU011248 Versus Interferon-Alfa As First-Line Systemic Therapy For Patients With Metastatic Renal Cell…
