Renal

Lungs 01 Jan 2013

A Study of LY2127399 in Patients with Systemic Lupus Erythematosus

The purpose of this SLE study is to evaluate the efficacy, safety and tolerability of two different doses of LY2127399 administered in addition to standard of care therapy in patients with active SLE. Official Title A Phase 3, Multicenter, Randomised, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of…
Research and Trials 01 Jan 2013

Incident Dialysis

Randomised trial to evaluate the efficacy and safety of Cinacalcet treatment in combination with low dose vitamin D for the treatment of subjects with secondary…
Heart 01 Jan 2013

The Effect of Atorvastatin on Postoperative Renal Function After Cardiac Surgery

Atorvastatin might reduce the oxidative stress that occurs during cardiopulmonary bypass, and thus, prevent or reduce the magnitude of acute kidney dysfunction in those patients…
An Investigation of N-Acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery
Heart 01 Jan 2013

An Investigation of N-Acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery

Patients with abnormal kidney function are at increased risk for complications following heart surgery, including worsening kidney function possibly requiring dialysis, a prolonged stay in the critical care unit and hospital, and the increased risk of death. Prior attempts at kidney protection for heart surgery patients have had mixed results.
Research and Trials 01 Jan 2013

The Role of Reactive Oxygen Species in Ischaemia-Reperfusion Injury of the Transplanted Kidney

Measurement of reactive oxygen species production and antioxidant system status before and directly after reperfusion of the transplanted kidney and influence of oxidant stress on kidney function in 2 and 6 weeks. Official TitleThe Role of Reactive Oxygen Species in Ischaemia-Reperfusion Injury of the Transplanted Kidney.
Research and Trials 01 Jan 2013

Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients

Alemtuzumab is a man-made antibody used to treat certain blood disorders. This study will evaluate treatment of kidney transplant recipients with alemtuzumab and other immune system suppressing medications with or without infusions of bone marrow stem cells from the kidney donor. The purpose of this study is to find out…
Research and Trials 01 Jan 2013

Far Infrared Treatment for Kidney Diseases

Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided into acute and chronic forms; either form may be due to a large number of other medical problems. Official Title Phase 1 Study to Examine the Use of Far Infrared Radiation…
Research and Trials 01 Jan 2013

Kidney Stone Structural Analysis By Helical Computed Tomography (CT)

Current practices of the diagnosis of urinary stones gives little information on the probable fragility of stones using shock wave lithotripsy (SWL), and many patients receive more SW’s than is necessary to break up their stones. Indeed, some patients are treated with SWL when their stones cannot be fragmented using…
Research and Trials 01 Jan 2013

Randomised Controlled Trial of Vitamin D3 in Diabetic Kidney Disease

This study will assess the effects of vitamin D3 supplementation (cholecalciferol; 2000 IU daily) on serum calcium levels, circulating vitamin D levels, and markers of kidney disease and cardiovascular risk among people with diabetes mellitus and early kidney disease. Eligibility criteria include type 2 diabetes and stage 1-2 chronic kidney…