Lungs
01 Jan 2013
A Study of LY2127399 in Patients with Systemic Lupus Erythematosus
The purpose of this SLE study is to evaluate the efficacy, safety and tolerability of two different doses of LY2127399 administered in addition to standard of care therapy in patients with active SLE. Official Title A Phase 3, Multicenter, Randomised, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of…
Research and Trials
01 Jan 2013
Incident Dialysis
Randomised trial to evaluate the efficacy and safety of Cinacalcet treatment in combination with low dose vitamin D for the treatment of subjects with secondary…
Heart
01 Jan 2013
The Effect of Atorvastatin on Postoperative Renal Function After Cardiac Surgery
Atorvastatin might reduce the oxidative stress that occurs during cardiopulmonary bypass, and thus, prevent or reduce the magnitude of acute kidney dysfunction in those patients…
Heart
01 Jan 2013
An Investigation of N-Acetylcysteine and Fenoldopam as Renal Protection Agents for Cardiac Surgery
Patients with abnormal kidney function are at increased risk for complications following heart surgery, including worsening kidney function possibly requiring dialysis, a prolonged stay in the critical care unit and hospital, and the increased risk of death. Prior attempts at kidney protection for heart surgery patients have had mixed results.
Research and Trials
01 Jan 2013
The Role of Reactive Oxygen Species in Ischaemia-Reperfusion Injury of the Transplanted Kidney
Measurement of reactive oxygen species production and antioxidant system status before and directly after reperfusion of the transplanted kidney and influence of oxidant stress on kidney function in 2 and 6 weeks.
Official TitleThe Role of Reactive Oxygen Species in Ischaemia-Reperfusion Injury of the Transplanted Kidney.
Research and Trials
01 Jan 2013
Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients
Alemtuzumab is a man-made antibody used to treat certain blood disorders. This study will evaluate treatment of kidney transplant recipients with alemtuzumab and other immune system suppressing medications with or without infusions of bone marrow stem cells from the kidney donor. The purpose of this study is to find out…
Research and Trials
01 Jan 2013
Far Infrared Treatment for Kidney Diseases
Renal failure or kidney failure is a situation in which the kidneys fail to function adequately. It is divided into acute and chronic forms; either form may be due to a large number of other medical problems. Official Title Phase 1 Study to Examine the Use of Far Infrared Radiation…
Research and Trials
01 Jan 2013
Kidney Stone Structural Analysis By Helical Computed Tomography (CT)
Current practices of the diagnosis of urinary stones gives little information on the probable fragility of stones using shock wave lithotripsy (SWL), and many patients receive more SW’s than is necessary to break up their stones. Indeed, some patients are treated with SWL when their stones cannot be fragmented using…
Research and Trials
01 Jan 2013
Randomised Controlled Trial of Vitamin D3 in Diabetic Kidney Disease
This study will assess the effects of vitamin D3 supplementation (cholecalciferol; 2000 IU daily) on serum calcium levels, circulating vitamin D levels, and markers of kidney disease and cardiovascular risk among people with diabetes mellitus and early kidney disease. Eligibility criteria include type 2 diabetes and stage 1-2 chronic kidney…