Mental Health
01 Jan 2013
Clinical Trial of Tolcapone for Cognition in Schizophrenia
The purpose of this study is to test whether the drug tolcapone improves the memory of patients with schizophrenia. The purpose of this study is to test whether the drug tolcapone improves the memory of patients with schizophrenia.The catecholaminergic system can enhance some aspects of cognitive function, such as working…
Mental Health
01 Jan 2013
Treatment for First-Episode Schizophrenia
The purpose of this study is to see if the newest class of antipsychotic medications can improve the course of patients with first-episode schizophrenia. Official Title Preventing Morbidity in First-Episode Schizophrenia Conditions – Schizophrenia Study Type Interventional Study Design Treatment, Randomized Further Details Schizophrenia patients generally respond very well…
Mental Health
01 Jan 2013
Genetic Study of Schizophrenia
The purpose of this study is to understand the role of genetics in the development of schizophrenia by studying heritable traits in families where at least one member has schizophrenia. Official Title A Neurobiological Investigation of Patients with Schizophrenia Spectrum Disorders and Their Siblings Conditions – Psychotic Disorder- Schizoaffective Disorder-…
Lungs
01 Jan 2013
Treatment of Pulmonary Sarcoidosis with Pentoxifylline
Sarcoidosis is a disease most commonly affecting the lungs, but it can also involve lymph nodes, skin, liver, spleen, eyes, bones, and glands. The cause of the disease is unknown. When it occurs it can produce an inflammatory reaction leading to irreversible organ damage and disability. Official Title Conditions –…
Lungs
01 Jan 2013
Lung Volume Reductions Surgery (LVRS) Study
The main objectives of this study is to see if a type of lung surgery, known as lung reduction surgery, in addition to standard medical treatment improves the quality of life, lung function, and reduces the high mortality associated with severe emphysema when compared to standard medical treatment alone. Another…
Lungs
01 Jan 2013
Tissue Collection from People with Cystic Fibrosis
This study will examine the relationship between bacterial products in lung infections in cystic fibrosis and disease severity. It will examine plasma and lung tissue from cystic fibrosis patients. Official Title Tissue Collection Protocol for Individuals with Cystic Fibrosis Conditions Cystic Fibrosis Study Type Observational Study Design Natural History…
Lungs
01 Jan 2013
Epidemiology of Surfactant Protein-B Deficiency
To determine the impact of surfactant protein B genetic mutations on the risk of respiratory distress syndrome in infancy. Official Title Conditions – Lung Diseases- Respiratory Distress Syndrome Study Type Observational Study Design Natural History, Case Control Further Details BACKGROUND: Respiratory distress syndrome (RDS) is a common cause…
Infections
01 Jan 2013
Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers with HIV
HIV infected women in South Africa have a high risk of tuberculosis (TB) infection. Children born to HIV infected mothers may be more likely to be exposed to and become infected with TB, and children infected with TB have a higher risk of developing severe disease than adults with TB.
Lungs
01 Jan 2013
Role of T-Cells in Asthma
This study will examine the movement of T cells (a type of white blood cell) from the blood to the lungs in patients with asthma after exposure to an allergen, such as cat dander or pollen. Asthma is in large part due to inflammation of the bronchi (the breathing tubes…
