Heart
01 Jan 2013
Gender, Obesity, C-Reactive Protein, and Oxidative Stress
This randomized placebo-controlled trial will test whether supplementing with vitamins C and E can lower markers of inflammation and oxidative stress in healthy adults. We will examine whether one antioxidant vitamin is more effective than another, and whether gender or body fat influence the treatment effects. We will also determine…
Lungs
01 Jan 2013
Sarcoid Genetic Analysis (SAGA)
To identify sarcoidosis susceptibility genes and to determine how these genes and environmental risk factors interact to cause sarcoidosis. Official Title Conditions – Lung Diseases- Sarcoidosis Study Type Observational Study Design Natural History, Defined Population Further Details BACKGROUND: Sarcoidosis is a rare systemic granulomatous disease that mainly affects…
Mental Health
01 Jan 2013
Behavioral Treatment, Drug Treatment, and Combined Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to determine the effectiveness of behavioral treatment, drug treatment, and combined treatment for children with Attention Deficit Hyperactivity Disorder (ADHD). This study will also examine the interactions between different levels of behavioral and drug treatments. Official Title ADHD Treatment: Comparative and Combined Dosage Effects…
Lungs
01 Jan 2013
Sample Collections from the Airways of Asthmatic Patients
Fiberoptic bronchoscopy is a procedure which involves passing a pencil-thin tube into the lung in order to collect fluid and cells from the airways. Fiberoptic bronchoscopy can collect cells from the walls of airways by gently brushing them (bronchial brushing). In addition, squirting small amounts of sterile water in to…
Lungs
01 Jan 2013
Nasal Irritation Study
This study seeks to document differences in nasal irritant sensitivity within the population. We are interested in knowing whether age, gender, and allergy status (nasal allergies) predict nasal irritant sensitivity. This is important in understanding symptom reporting patterns in air pollution situations (particularly in so-called “problem buildings”), as well as…
Mental Health
01 Jan 2013
Clinical Trial of Estrogen for Postpartum Depression
The purpose of this study is to evaluate the effectiveness of 17 beta-estradiol, a form of estrogen, in treating women with postpartum depression (PPD). The purpose of this study is to evaluate the effectiveness of 17 beta-estradiol, a form of estrogen, in treating women with postpartum depression (PPD). PPD causes…
Neurology
01 Jan 2013
Effect of Fluoxetine (Prozac) on Domestic Violence
This study will evaluate whether fluoxetine (Prozac), used together with traditional psychotherapy, can reduce aggression in people who are physically violent towards their spouses or significant others. Treatment for domestic violence has centered on behavioral therapies, such as anger management and self-control exercises. Recent studies have shown that fluoxetine-a drug…
Lungs
01 Jan 2013
Study Evaluating the Safety and Efficacy of Infliximab in Subjects with Moderate to Severe Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine the safety and efficacy of infliximab in patients with moderate to severe Chronic Obstructive Pulmonary Disease. Official Title A Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled Parallel Group, Dose Finding Study Evaluating the Safety and Efficacy of Infliximab Administration in Symptomatic Subjects with…
Lungs
01 Jan 2013
Study of the Disease Process of Lymphangioleiomyomatosis
Pulmonary lymphoangioleiomyomatosis (LAM) is a destructive lung disease typically affecting women of childbearing age. Currently, there is no effective therapy for the disease and the prognosis is poor. Official Title Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM) Conditions – Leiomyomatosis- Lung Disease- Pneumothorax- Tuberous Sclerosis Study Type Observational Study…
