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Safety and Immunogenicity of 2 Formulations of an Intramuscular A/H5N1 Pandemic Influenza Vaccine in Children

This is an open, randomised, multicentre clinical trial.Objectives:To describe the safety profiles during the 21 days following each primary and…

01 Jan 2013

A Phase III Trial to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

A Phase III Trial to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) Extended Release (ER) in Patients With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

The purpose of this trial is to evaluate the effectiveness (level of pain control) and safety of orally administrated CG5503…

01 Jan 2013

Treatment of Deficient Subclass or Anti-Polysaccharide Antibody

There is no consensus on the treatment of patients with recurrent infections and isolated immunoglobulin G (IgG)-subclass deficiency and/or selective…

01 Jan 2013

Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old

Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old

Main goal of this study is to compare the occurrence of serious adverse events (SAEs) between the herpes simplex (gD2-AS04)…

01 Jan 2013

A Safety Study of Two Intratumour Doses of Coxsackievirus Type A21 in Melanoma Patients.

A Safety Study of Two Intratumour Doses of Coxsackievirus Type A21 in Melanoma Patients.

The purpose of the study is to determine the safety and tolerability of two doses of Coxsackievirus A21, administered 48…

01 Jan 2013

Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Cutaneous Squamous Cell Carcinoma In Situ

Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Cutaneous Squamous Cell Carcinoma In Situ

The purpose of this study is to determine whether the topical application of PEP005 is safe and effective for the…

01 Jan 2013

Vaccine Therapy for Patients With Stage III Melanoma

This is a Phase 3 study in patients with melanoma that has spread to the lymph nodes (stage III), and…

01 Jan 2013

Safety Study of Oral BTA9881 to Treat Respiratory Syncytial Virus Infections

This is a placebo-controlled, double-blind, randomised, single dose escalation Phase I clinical trial to determine the safety and tolerability of…

01 Jan 2013

Panic Disorder and Cardiac Risk

Panic Disorder and Cardiac Risk

The reason for increased cardiac mortality in panic disorder has not been precisely identified, but possibly is due to chronic…

01 Jan 2013